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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNSNGPLMEH GKRRVAYYYD SNIGNYYYGQ GHVMKPHRIR MTHHLVLNYG LYRNLEIFRP

70 80 90 100 110 120
FPASFEDMTR FHSDEYMTFL KSANPDNLKS FNKQMLKFNV GEDCPLFDGL YEFCQLSSGG

130 140 150 160 170 180
SLAAATKLNK QKVDIAINWM GGLHHAKKSE ASGFCYTNDI VLGILELLKY HKRVLYVDID

190 200 210 220 230 240
VHHGDGVEEA FYTTDRVMTV SFHKYGDFFP GTGDLKDIGA GKGKLYSVNV PLRDGITDVS

250 260 270 280 290 300
YQSIFKPIMT KVMERFDPCA VVLQCGADSL NGDRLGPFNL TLKGHGECAR FFRSYNVPLM

310 320 330 340 350 360
MVGGGGYTPR NVARCWTYET SIAVDKEVPN ELPYNDYFEY FGPNYRLHIE SSNAANENSS

370 380 390 400 410 420
DMLAKLQTDV IANLEQLTFV PSVQMRPIPE DALSALNDDS LIADQANPDK RLPPQITDGM

430 440 450 460
IQDDGDFYDG EREGDDRRNE SDAKRAAQFE SEGGEKRQKT E


References and documentation are available.

Number of amino acids: 461 Molecular weight: 52137.63 Theoretical pI: 5.50
Amino acid composition: 
Ala (A) 27 5.9% Arg (R) 24 5.2% Asn (N) 28 6.1% Asp (D) 37 8.0% Cys (C) 7 1.5% Gln (Q) 14 3.0% Glu (E) 27 5.9% Gly (G) 39 8.5% His (H) 14 3.0% Ile (I) 19 4.1% Leu (L) 38 8.2% Lys (K) 26 5.6% Met (M) 16 3.5% Phe (F) 24 5.2% Pro (P) 22 4.8% Ser (S) 27 5.9% Thr (T) 19 4.1% Trp (W) 2 0.4% Tyr (Y) 25 5.4% Val (V) 26 5.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 64 Total number of positively charged residues (Arg + Lys): 50 Atomic composition: Carbon C 2311 Hydrogen H 3529 Nitrogen N 631 Oxygen O 703 Sulfur S 23 Formula: C2311H3529N631O703S23 Total number of atoms: 7197 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 48625 Abs 0.1% (=1 g/l) 0.933, assuming all pairs of Cys residues form cystines Ext. coefficient 48250 Abs 0.1% (=1 g/l) 0.925, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 37.20 This classifies the protein as stable. Aliphatic index: 70.43 Grand average of hydropathicity (GRAVY): -0.526