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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNSSNDLSDE LIRRLSVGGA LEEVIASEMF EDSIDVETEA EPDDIIIVHM DIREPLSMLK

70 80 90 100 110 120
SLVEQKIGVC LNYYTFWLQD AQELESHKNL VDQCVKGEGL VQINVQIQTI RKRINIADVL

130 140 150 160 170 180
KPTEAALAAL AEEVVGQLSP PETASQKSSS SESPIKTPLK RMHKEDSEEE SVEGKDVKPV

190 200 210 220 230 240
LNWVLDSKFK REQIRLKIPE AANEWTHAHV TYWLEWAVKQ FELVGINMSD WQMNGQELCA

250 260 270 280 290 300
MTHEEFNQKL PRDPGNIFWT HLQLLKECNF VSVVHKRAEE QRKPKQPRIM SANSISTNSG

310 320 330 340 350 360
GSLSLEQRIM RKSYQSVKSS DSVESTTSSM NPSNYTTIGS GNNGQVQLWQ FLLEILTDCE

370 380 390 400 410 420
HTDVIEWVGT EGEFKLTDPD RVARLWGEKK NKPAMNYEKL SRALRYYYDG DMISKVSGKR

430 440 450 460
FAYKFDCDLK LLIGYDANEL STLVSEGKTA PERVAATETI TEDT


References and documentation are available.

Number of amino acids: 464 Molecular weight: 52644.46 Theoretical pI: 5.01
Amino acid composition: 
Ala (A) 26 5.6% Arg (R) 20 4.3% Asn (N) 22 4.7% Asp (D) 26 5.6% Cys (C) 6 1.3% Gln (Q) 22 4.7% Glu (E) 48 10.3% Gly (G) 22 4.7% His (H) 9 1.9% Ile (I) 27 5.8% Leu (L) 42 9.1% Lys (K) 33 7.1% Met (M) 13 2.8% Phe (F) 11 2.4% Pro (P) 17 3.7% Ser (S) 42 9.1% Thr (T) 25 5.4% Trp (W) 10 2.2% Tyr (Y) 11 2.4% Val (V) 32 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 74 Total number of positively charged residues (Arg + Lys): 53 Atomic composition: Carbon C 2312 Hydrogen H 3667 Nitrogen N 629 Oxygen O 735 Sulfur S 19 Formula: C2312H3667N629O735S19 Total number of atoms: 7362 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 71765 Abs 0.1% (=1 g/l) 1.363, assuming all pairs of Cys residues form cystines Ext. coefficient 71390 Abs 0.1% (=1 g/l) 1.356, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.10 This classifies the protein as unstable. Aliphatic index: 83.60 Grand average of hydropathicity (GRAVY): -0.513