ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNSTNSTNST TTATSTNTST QQVVTSLVSN GTIFGVFVIA FLILRIKLKR IYEPKSSFNL 

        70         80         90        100        110        120 
INEEKKPEPL PQGVWQWLKP LLKKSDNFVI QQAGLDGYFF LRYLFIIAIY CAVSMSYIFP 

       130        140        150        160        170        180 
ILLSINASNG NHESGLNQLA YQNVKHRGRY FAHVFCGWIF FWGFLYIIYR ELYFYTSMKQ 

       190        200        210        220        230        240 
AVLASPRYAK KLSSRTVLFQ TVPKQYLSEE EFSKLFDGVK RVWIARGSGS IEAMVKARDN 

       250        260        270        280        290        300 
MAIQLEGAET KYLKAALKKI KKLNKKSPQL SVSDNIAEYV PDKKRPHHKI NKVAKFFFGK 

       310        320        330        340        350        360 
KVDTISYIKE ELPKLNQKVK ALQEDHENSS PFNSVFVEFE SQYQAQVAAQ ITTYHAPLFM 

       370        380        390        400        410        420 
TPVYIGIEPS DVVWFNLRMF WWERLGREVS AVSAIVALVI LWAFPVAFVG MISNITSLTN 

       430        440        450        460        470        480 
EVKWLKFIYK LPKQLLGLLT SLAPTVALAV LMSFLPKFIR GMAITQGAPS KQNVEYFTQQ 

       490        500        510        520        530        540 
AYFAFQVIQV FLVTTLSSAA TSTVTEIVKE PTKAMDLLAS NLPKASNFFM SYVILQGLSI 

       550        560        570        580        590        600 
SSGALLQIVP LILFYVLGAF LDGTVRKKWN RFCGLSSMQW GTAFPVYTNL AVITFSYSII 

       610        620        630        640        650        660 
SPLILLFAAV AFFLLYIAYL YNLTYVYQES PDARGIYYPR ALFQTIVGIY IGQICLLGLF 

       670        680        690        700        710        720 
AVGKGWGPIV LQVIGICVTV LIHLHLSAAF DHLSKVIPVD TMKPLDGVSD TPSFKNIYKG 

       730        740        750        760        770        780 
IESTKVKKNT FGANIDMDGI KELPEFPIKK YHKRSESVTE QQVENSIFSE NTFEYQFNPA 

       790        800        810        820        830        840 
NEANADGHAI NAENLIEDVP LLADGDTMKI PPAPWWKRFL KPHIYYSYKA VKSRLPEIYG 

       850        860        870        880        890        900 
LVDPDERVND FDISHAYDYP AVSAQCPELW IPRDPFGFSK LLISDVSGVV EMNDENATID 

       910        920        930        940        950 
ENLKFTLRDV PPPYNDVKDE ANGEANGEFD TASKENNPFA DPKYKEEESR SAV 

References and documentation are available.

Number of amino acids: 953

Molecular weight: 107672.54

Theoretical pI: 8.74

Amino acid composition: 
Ala (A)  73	  7.7%
Arg (R)  27	  2.8%
Asn (N)  48	  5.0%
Asp (D)  36	  3.8%
Cys (C)   6	  0.6%
Gln (Q)  37	  3.9%
Glu (E)  51	  5.4%
Gly (G)  46	  4.8%
His (H)  14	  1.5%
Ile (I)  70	  7.3%
Leu (L)  91	  9.5%
Lys (K)  69	  7.2%
Met (M)  17	  1.8%
Phe (F)  62	  6.5%
Pro (P)  51	  5.4%
Ser (S)  73	  7.7%
Thr (T)  48	  5.0%
Trp (W)  16	  1.7%
Tyr (Y)  45	  4.7%
Val (V)  73	  7.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 87
Total number of positively charged residues (Arg + Lys): 96

Atomic composition:

Carbon      C	      4986
Hydrogen    H	      7668
Nitrogen    N	      1232
Oxygen      O	      1379
Sulfur      S	        23

Formula: C4986H7668N1232O1379S23
Total number of atoms: 15288

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   155425
Abs 0.1% (=1 g/l)   1.443, assuming all pairs of Cys residues form cystines


Ext. coefficient   155050
Abs 0.1% (=1 g/l)   1.440, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.58
This classifies the protein as stable.



Aliphatic index: 95.76

Grand average of hydropathicity (GRAVY): 0.018