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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNTNPVTNGF VKPVPTEEEQ AKIEEVRKLL GPLPEKLSSF CSDDAVLRYL RARNWHVKKA

70 80 90 100 110 120
TKMLKETLKW RVQYKPEEIC WEEVAGEAET GKIYRSSCVD KLGRPVLIMR PSVENSKSVK

130 140 150 160 170 180
GQIRYLVYCM ENAVQNLPPG EEQMVWMIDF HGYSLANVSL RTTKETAHVL QEHYPERLAF

190 200 210 220 230 240
AVLYNPPKFF EPFWKVARPF LEPKTRNKVK FVYSDDPNTK VIMEENFDME KMELAFGGND

250 260 270 280 290 300
DSGFNIEKHS ERMKEDDKKR LASLEGIVSA SLDSLSILSV SDGTASNSAH PSSHDVSEDE


H


References and documentation are available.

Number of amino acids: 301 Molecular weight: 34433.17 Theoretical pI: 5.85
Amino acid composition: 
Ala (A) 17 5.6% Arg (R) 15 5.0% Asn (N) 15 5.0% Asp (D) 15 5.0% Cys (C) 4 1.3% Gln (Q) 6 2.0% Glu (E) 32 10.6% Gly (G) 13 4.3% His (H) 8 2.7% Ile (I) 10 3.3% Leu (L) 24 8.0% Lys (K) 26 8.6% Met (M) 10 3.3% Phe (F) 12 4.0% Pro (P) 18 6.0% Ser (S) 25 8.3% Thr (T) 12 4.0% Trp (W) 5 1.7% Tyr (Y) 9 3.0% Val (V) 25 8.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 47 Total number of positively charged residues (Arg + Lys): 41 Atomic composition: Carbon C 1529 Hydrogen H 2394 Nitrogen N 414 Oxygen O 463 Sulfur S 14 Formula: C1529H2394N414O463S14 Total number of atoms: 4814 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41160 Abs 0.1% (=1 g/l) 1.195, assuming all pairs of Cys residues form cystines Ext. coefficient 40910 Abs 0.1% (=1 g/l) 1.188, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.69 This classifies the protein as unstable. Aliphatic index: 73.79 Grand average of hydropathicity (GRAVY): -0.587