ProtParam
User-provided sequence:
10 20 30 40 50 60
MNTPQISLYE PGTILTVGSH HAKIIKYLTS GGFAQVYTAE ISPPDPYSNA NIACLKRVIV
70 80 90 100 110 120
PHKQGLNTLR AEVDAMKLLR NNKHVVSYID SHAARSVNGI AYEVFVLMEF CERGGLIDFM
130 140 150 160 170 180
NTRLQNRLQE SEILEIMSQT VQGITAMHAL QPPLIHRDIK IENVLISHDG LYKVCDFGSV
190 200 210 220 230 240
SGVIRPPRNT QEFNYVQHDI LTNTTAQYRS PEMIDLYRGL PIDEKSDIWA LGVFLYKICY
250 260 270 280 290 300
YTTPFEKSGE AGILHARYQY PSFPQYSDRL KNLIRLMLME APSQRPNICQ VLEEVSRLQN
310 320 330 340 350 360
KPCPIRNFYL LRAMNQNANT QLAGEPSSTT YVPTQKFIPV QSLQSINQPP NMMPVTHVST
370 380 390 400 410 420
TPNLGTFPIS INDNNKTEVT AHAGLQVGSH SNLTSPLMKT KSVPLSDEFA SLYYKELHPF
430 440 450 460 470 480
QKSQTFKSVE SFQSPQRKSM PPLSLTPVNN DIFDRVSAIN RPNNYVDSET QTIDNMAVPN
490 500 510 520 530 540
LKLSPTITSK SLSSTKEIAA PDNINGSKIV RSLSSKLKKV ITGESRGNSP IKSRQNTGDS
550 560 570 580 590 600
IRSAFGKLRH GFTGNSVNNS RSASFDNNNV NGNGNNTNRR LVSSSTSSFP KFNSDTKRKE
610 620 630 640 650 660
ESDKNQRLEK RRSMPPSILS DFDQHERNNS RTGSRDYYRS HSPVKKTQAS AKTTSKPTLI
670 680 690 700 710 720
PDNGNVNINQ EKKESIQRRV HNLLKSSDDP VTYKSASGYG KYTDIGTETS NRHSSVRITP
730 740 750 760 770 780
ITEEKFKKTL KDGVLDIKTK SNGKDKSRPP RPPPKPLHLR TEIQKIRNFS RLQSKKLPIE
790 800 810
RISSEATETI VDVNVDDLEA DFRKRFPSKV
References and
documentation are available.
Number of amino acids: 810
Molecular weight: 91032.06
Theoretical pI: 9.63
Total number of negatively charged residues (Asp + Glu): 77
Total number of positively charged residues (Arg + Lys): 108
Atomic composition:
Carbon C 3990
Hydrogen H 6403
Nitrogen N 1157
Oxygen O 1234
Sulfur S 22
Formula: C
3990H
6403N
1157O
1234S
22
Total number of atoms: 12806
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 44615
Abs 0.1% (=1 g/l) 0.490, assuming all pairs of Cys residues form cystines
Ext. coefficient 44240
Abs 0.1% (=1 g/l) 0.486, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 49.22
This classifies the protein as unstable.
Aliphatic index: 76.04
Grand average of hydropathicity (GRAVY): -0.648