ProtParam
User-provided sequence:
10 20 30 40 50 60
MNTSPKMEME MKMETKAAPE AGMIKKSNEE WRTVLSPEQF KILREKSIEK RGSGEYVKLF
70 80 90 100 110 120
EEGIYCCVGC GNPVYKSTTK FDSGCGWPAF FDAIPGAINR TEERAGLRYE ITCTKCDGHL
130 140 150
GHVLKNEGFP TPTDERHCVN SVALKFSSAI TSQ
References and
documentation are available.
Number of amino acids: 153
Molecular weight: 17097.54
Theoretical pI: 6.82
Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 21
Atomic composition:
Carbon C 746
Hydrogen H 1174
Nitrogen N 204
Oxygen O 230
Sulfur S 13
Formula: C
746H
1174N
204O
230S
13
Total number of atoms: 2367
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 17335
Abs 0.1% (=1 g/l) 1.014, assuming all pairs of Cys residues form cystines
Ext. coefficient 16960
Abs 0.1% (=1 g/l) 0.992, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 44.96
This classifies the protein as unstable.
Aliphatic index: 57.39
Grand average of hydropathicity (GRAVY): -0.536