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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNVTSLFSFT SPAVKRLLGW KQGDEEEKWA EKAVDALVKK LKKKKGAMEE LEKALSCPGQ

70 80 90 100 110 120
PSNCVTIPRS LDGRLQVSHR KGLPHVIYCR VWRWPDLQSH HELKPLECCE FPFGSKQKEV

130 140 150 160 170 180
CINPYHYKRV ESPVLPPVLV PRHSEYNPQH SLLAQFRNLG QNEPHMPLNA TFPDSFQQPH

190 200 210 220 230 240
SHPFPQSPNS SYPNSPGSSS STYPHSPTSS DPGSPFQMPA DTPPPAYLPP EDPMAQDGSQ

250 260 270 280 290 300
PMDTNMTNMT APTLPAEINR GDVQAVAYEE PKHWCSIVYY ELNNRVGEAF HASSTSVLVD

310 320 330 340 350 360
GFTDPSNNKN RFCLGLLSNV NRNSTIENTR RHIGKGVHLY YVGGEVYAEC LSDSSIFVQS

370 380 390 400 410 420
RNCNYHHGFH PTTVCKIPSG CSLKIFNNQE FAQLLAQSVN HGFETVYELT KMCTIRMSFV

430 440 450 460
KGWGAEYHRQ DVTSTPCWIE IHPHGPLQWL DKVLTQMGSP HNPISSVS


References and documentation are available.

Number of amino acids: 468 Molecular weight: 52532.29 Theoretical pI: 6.90
Amino acid composition: 
Ala (A) 21 4.5% Arg (R) 18 3.8% Asn (N) 27 5.8% Asp (D) 16 3.4% Cys (C) 14 3.0% Gln (Q) 22 4.7% Glu (E) 28 6.0% Gly (G) 26 5.6% His (H) 23 4.9% Ile (I) 14 3.0% Leu (L) 35 7.5% Lys (K) 24 5.1% Met (M) 11 2.4% Phe (F) 18 3.8% Pro (P) 46 9.8% Ser (S) 47 10.0% Thr (T) 23 4.9% Trp (W) 8 1.7% Tyr (Y) 16 3.4% Val (V) 31 6.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 44 Total number of positively charged residues (Arg + Lys): 42 Atomic composition: Carbon C 2330 Hydrogen H 3555 Nitrogen N 649 Oxygen O 692 Sulfur S 25 Formula: C2330H3555N649O692S25 Total number of atoms: 7251 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 68715 Abs 0.1% (=1 g/l) 1.308, assuming all pairs of Cys residues form cystines Ext. coefficient 67840 Abs 0.1% (=1 g/l) 1.291, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 60.82 This classifies the protein as unstable. Aliphatic index: 64.53 Grand average of hydropathicity (GRAVY): -0.575