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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MNYGVEKLKL KYSKHGCITC KIRKKRCSED KPVCRDCRRL SFPCIYISES VDKQSLKKIK

70 80 90 100 110 120
ADIQHQLISK KRKHAPDSAQ KAAVATRTRR VGSDEQDNQV YLSKPLEDCI SQKLDSMGLQ

130 140 150 160 170 180
LYNYYRSHLA NIISIAPMNQ NYYLNIFLPM AHENDGILFA ILAWSANHLS ISSSNELRKD

190 200 210 220 230 240
EIFVNLANKY TYMSLSHLKT NEGSSACAKL GFLYSLAQIL ILCGSEICQG DVKFWKILLN

250 260 270 280 290 300
IGKNLIENHV GKDVSRILTT TTEEPSLEER IIFPNFNSVV KYWLIVNFIY HDILNFNTTS

310 320 330 340 350 360
FPIEQYEKFF QRDQNSLPSS ANFIESIDSP IEEIDPLIGI NKPILLLLGQ VTNLTRFLQT

370 380 390 400 410 420
MEQEEMLEHG DKILSLQVEI YKLQPSLMAL EHLDDEKKFY YLELFEIMKI STLMFFQLTL

430 440 450 460 470 480
LKIDKDSLEL QILRNKLDSK LDKVIGTFLE GSLCFPLFIY GVCIQVEDME KKIDLEAKFD

490 500 510 520
DILKRYKCYN FQNARLLIRK IWQNEADGIS EHDLVHMIDE LDYNINFA


References and documentation are available.

Number of amino acids: 528 Molecular weight: 61223.86 Theoretical pI: 6.27
Amino acid composition: 
Ala (A) 22 4.2% Arg (R) 19 3.6% Asn (N) 31 5.9% Asp (D) 32 6.1% Cys (C) 13 2.5% Gln (Q) 24 4.5% Glu (E) 37 7.0% Gly (G) 18 3.4% His (H) 13 2.5% Ile (I) 52 9.8% Leu (L) 67 12.7% Lys (K) 45 8.5% Met (M) 12 2.3% Phe (F) 25 4.7% Pro (P) 15 2.8% Ser (S) 41 7.8% Thr (T) 17 3.2% Trp (W) 4 0.8% Tyr (Y) 22 4.2% Val (V) 19 3.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 69 Total number of positively charged residues (Arg + Lys): 64 Atomic composition: Carbon C 2762 Hydrogen H 4367 Nitrogen N 715 Oxygen O 802 Sulfur S 25 Formula: C2762H4367N715O802S25 Total number of atoms: 8671 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 55530 Abs 0.1% (=1 g/l) 0.907, assuming all pairs of Cys residues form cystines Ext. coefficient 54780 Abs 0.1% (=1 g/l) 0.895, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.30 This classifies the protein as unstable. Aliphatic index: 102.50 Grand average of hydropathicity (GRAVY): -0.211