ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPAVGGIPPS GGNRKVYPGN LTLYVTVTCV VAAMGGLIFG YDIGISGGVT SMDSFLKKFF 

        70         80         90        100        110        120 
PSVYRKKKAD ESSNQYCQYD SQTLTMFTSS LYLAALIASL VASTITRKFG RKLSMLFGGV 

       130        140        150        160        170        180 
LFCAGAIING AAKAVWMLIL GRILLGFGIG FANQSVPLYL SEMAPYKYRG ALNIGFQLSI 

       190        200        210        220        230        240 
TIGILVANVL NYFFAKIKGG WGWRLSLGGA MVPALIITVG SLVLPDTPNS MIERGQHEEA 

       250        260        270        280        290        300 
RAHLKRVRGV EDVDEEFTDL VHASEDSKKV EHPWRNLLQR KYRPHLSMAI AIPFFQQLTG 

       310        320        330        340        350        360 
INVIMFYAPV LFDTIGFGSD AALMSAVITG LVNVFATMVS IYGVDKWGRR FLFLEGGVQM 

       370        380        390        400        410        420 
LICQAIVAAC IGAKFGVDGA PGDLPQWYAV VVVLFICIYV SGFAWSWGPL GWLVPSEIFP 

       430        440        450        460        470        480 
LEIRSAAQSV NVSVNMFFTF VVAQVFLIML CHLKFGLFIF FSFFVLIMSI FVYYFLPETK 

       490        500        510        520 
GIPIEEMGQV WKQHWYWSRY VVDEDYPNGG LEMGKEGRIP KNV 

References and documentation are available.

Number of amino acids: 523

Molecular weight: 57768.91

Theoretical pI: 8.87

Amino acid composition: 
Ala (A)  40	  7.6%
Arg (R)  19	  3.6%
Asn (N)  16	  3.1%
Asp (D)  16	  3.1%
Cys (C)   7	  1.3%
Gln (Q)  16	  3.1%
Glu (E)  19	  3.6%
Gly (G)  53	 10.1%
His (H)   7	  1.3%
Ile (I)  40	  7.6%
Leu (L)  51	  9.8%
Lys (K)  23	  4.4%
Met (M)  19	  3.6%
Phe (F)  38	  7.3%
Pro (P)  23	  4.4%
Ser (S)  34	  6.5%
Thr (T)  19	  3.6%
Trp (W)  12	  2.3%
Tyr (Y)  21	  4.0%
Val (V)  50	  9.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 35
Total number of positively charged residues (Arg + Lys): 42

Atomic composition:

Carbon      C	      2691
Hydrogen    H	      4123
Nitrogen    N	       661
Oxygen      O	       700
Sulfur      S	        26

Formula: C2691H4123N661O700S26
Total number of atoms: 8201

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    97665
Abs 0.1% (=1 g/l)   1.691, assuming all pairs of Cys residues form cystines


Ext. coefficient    97290
Abs 0.1% (=1 g/l)   1.684, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.68
This classifies the protein as stable.



Aliphatic index: 103.23

Grand average of hydropathicity (GRAVY): 0.472