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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPCLLPSLLR ATRAALPLLS PPRVVAASAS QRLLSAPAQP AASRSSMDSA EELLAPLRLA

70 80 90 100 110 120
VRQQGDFVRK LKEDKAPQVD VDRAVAELKA RKRVLEAKEL ALQPKDDIVD RAKMEDTLKR

130 140 150 160 170 180
RFFYDQAFAI YGGVSGLYDF GPVGCALKNN IIQAWRQHFI QEEQILEIDC TMLTPEPVLK

190 200 210 220 230 240
TSGHVDKFAD FMVKDVKNGE CFRADHLLKA HLQKLMSDKK CSAEKKSEME SVLAQLDNYG

250 260 270 280 290 300
QQELADLFVN YNVKSPTTGN DLSPPVPFNL MFQTFIGPGG NMPGYLRPET AQGIFLNFKR

310 320 330 340 350 360
LLEFNQGKLP FAAAQIGNSF RNEISPRSGL IRVREFTMAE IEHFVDPTEK DHPKFQSVAD

370 380 390 400 410 420
LCLYLYSAKA QVTGQSARKM RLGDAVEQGV INNSVLGYFI GRIYLYLTKV GISPDKLRFR

430 440 450 460 470 480
QHMENEMAHY ACDCWDAESK TSYGWIEIVG CADRSCYDLS CHARATKVPL VAEKPLKEPK

490 500 510 520 530 540
TVNVVQFEPN KGAVGKAYKK DAKLVLEYLS ACDECYISEM ELLLSEKGEF TIETEGKTFQ

550 560 570 580 590 600
LTKDMVSVKR FQKTLHVEEV VPSVIEPSFG LGRIMYTILE HTFHVREGDE QRTFFSFPAV

610 620 630 640 650 660
VAPFKCSVLP LSQNQEFMPF VKELSEALTR NGVSHKVDDS SGSIGRRYAR TDEIGVAFGI

670 680 690 700 710 720
TIDFDTVNKT PHTATLRDRD SMRQIRAEVS ELPSVVRDLA NGNITWADVE ARYPLFEGQE


TGKKETVEE


References and documentation are available.

Number of amino acids: 729 Molecular weight: 81850.74 Theoretical pI: 6.24
Amino acid composition: 
Ala (A) 61 8.4% Arg (R) 43 5.9% Asn (N) 23 3.2% Asp (D) 42 5.8% Cys (C) 14 1.9% Gln (Q) 32 4.4% Glu (E) 57 7.8% Gly (G) 41 5.6% His (H) 14 1.9% Ile (I) 30 4.1% Leu (L) 69 9.5% Lys (K) 50 6.9% Met (M) 18 2.5% Phe (F) 38 5.2% Pro (P) 38 5.2% Ser (S) 46 6.3% Thr (T) 34 4.7% Trp (W) 4 0.5% Tyr (Y) 20 2.7% Val (V) 55 7.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 99 Total number of positively charged residues (Arg + Lys): 93 Atomic composition: Carbon C 3643 Hydrogen H 5759 Nitrogen N 995 Oxygen O 1083 Sulfur S 32 Formula: C3643H5759N995O1083S32 Total number of atoms: 11512 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 52675 Abs 0.1% (=1 g/l) 0.644, assuming all pairs of Cys residues form cystines Ext. coefficient 51800 Abs 0.1% (=1 g/l) 0.633, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 49.26 This classifies the protein as unstable. Aliphatic index: 83.21 Grand average of hydropathicity (GRAVY): -0.310