ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPDETNFTIE DIEPRPDALR GLDTQFLQDN TALVQAYRGL DWSDISSLTQ MVDVIEQTVV 

        70         80         90        100        110        120 
KYGNPNDSIK LALETILWQI LRKYPLLFGF WKRFATIEYQ LFGLKKSIAV LATSVKWFPT 

       130        140        150        160        170        180 
SLELWCDYLN VLCVNNPNET DFIRNNFEIA KDLIGKQFLS HPFWDKFIEF EVGQKNWHNV 

       190        200        210        220        230        240 
QRIYEYIIEV PLHQYARFFT SYKKFLNEKN LKTTRNIDIV LRKTQTTVNE IWQFESKIKQ 

       250        260        270        280        290        300 
PFFNLGQVLN DDLENWSRYL KFVTDPSKSL DKEFVMSVFD RCLIPCLYHE NTWMMYIKWL 

       310        320        330        340        350        360 
TKKNISDEVV VDIYQKANTF LPLDFKTLRY DFLRFLKRKY RSNNTLFNNI FNETVSRYLK 

       370        380        390        400        410        420 
IWPNDILLMT EYLCMLKRHS FKNSLDQSPK EILEKQTSFT KILETSITNY INNQIDAKVH 

       430        440        450        460        470        480 
LQTLINDKNL SIVVVELIKT TWLVLKNNMQ TRKYFNLYQK NILIKNSVPF WLTYYKFEKS 

       490        500        510        520        530        540 
NVNFTKLNKF IRELGVEIYL PTTVMNDILT DYKTFYLTHS NIVTYESSII DSNTFDPILY 

       550        560        570        580        590        600 
PELKMSNPKY DPVLNTTANV DWHKKTEWKE AGHIGITTER PQISNSIIEC NSGTLIQKPI 

       610        620 
SLPNFRNLEK INQVKINDLY TEEFLKEGK 

References and documentation are available.

Number of amino acids: 629

Molecular weight: 74748.11

Theoretical pI: 8.50

Amino acid composition: 
Ala (A)  13	  2.1%
Arg (R)  22	  3.5%
Asn (N)  54	  8.6%
Asp (D)  34	  5.4%
Cys (C)   6	  1.0%
Gln (Q)  25	  4.0%
Glu (E)  39	  6.2%
Gly (G)  13	  2.1%
His (H)   9	  1.4%
Ile (I)  53	  8.4%
Leu (L)  69	 11.0%
Lys (K)  56	  8.9%
Met (M)  10	  1.6%
Phe (F)  39	  6.2%
Pro (P)  24	  3.8%
Ser (S)  34	  5.4%
Thr (T)  49	  7.8%
Trp (W)  16	  2.5%
Tyr (Y)  29	  4.6%
Val (V)  35	  5.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 73
Total number of positively charged residues (Arg + Lys): 78

Atomic composition:

Carbon      C	      3440
Hydrogen    H	      5302
Nitrogen    N	       864
Oxygen      O	       967
Sulfur      S	        16

Formula: C3440H5302N864O967S16
Total number of atoms: 10589

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   131585
Abs 0.1% (=1 g/l)   1.760, assuming all pairs of Cys residues form cystines


Ext. coefficient   131210
Abs 0.1% (=1 g/l)   1.755, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.05
This classifies the protein as stable.



Aliphatic index: 93.85

Grand average of hydropathicity (GRAVY): -0.352