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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPDLKSKTLS SQSLGAAIPP EIVYQILTYQ FRDLLRNDHP GTAEKFNENL TTFVKSNLTV

70 80 90 100 110 120
NKTFSHICQV LIYRYCNLTT AKRFHGLLQT LKGNRCLCNK IEVADFQELT SIGLGRSSEM

130 140 150 160 170 180
NKMIKNLTNE TLLEFLMLTK ANLREFLACE NIQDDLDDNI IKYILSPGKV LSVVDFCGCS

190 200 210 220 230 240
GTTFTESFIK ALDKYYPNKS IDQYRLEPIQ QNYQITCLGL NDCIDLPSHV LWKILKMLPE

250 260 270 280 290 300
LQKLDLSHTS IDDSTLYHGI PHWKNLTHLS LATCLQVTPR AVLEFFSHHP TITDPDNTST

310 320 330 340 350 360
LEWLNVSVIA HSSSWNEVHT MFLLKKLCQH GHNKTLQYLN IGGLPLHVAP SFGEDPISES

370 380 390 400 410 420
TYYYQCRDSL QFIKWNFPKL KSLSIKGNSI PISTLVEFLT PIDQDHPNCA QKLKFLNISG

430 440 450 460 470 480
NSYVNKWTIQ DSLLYTCSPS LVALEVSFDS WQQIEKLNDR HEIIAYRYKN PNSVIKDIST

490 500 510 520 530 540
AEQVKWKCYI DSSYGRRYWL YKTDPFLNRD DLDSKSNLTR YDFEGHKIIE IINQPDFLKF

550 560 570 580 590 600
AQSKIMLGCG LVPQSGIRRK LCYRDLKPPV SQFLNRKGAI SLGDTPLPII TPTLPRGGWR

610 620 630 640 650 660
IIHNEDDNNS HVEDSQNHVN AIPRRNSLLS RPTLRSNNGS SSANPFAINV SPASQIRDGL

670 680 690 700 710 720
YWDRSVHDLR ELSLQEQRIQ ELADEQQELR TIANFEETDD EYLHDPDLQR RRSQLHLFES

730 740 750 760 770 780
SRSRSGNKTR PSLTGEHSSS ASFLSFSHFN HLHKRKNYYF THPDEFVYDP KDPLTTQRYR

790 800
LHFEIVNEYQ VFGCIERGMY RYYSLKA


References and documentation are available.

Number of amino acids: 807 Molecular weight: 93122.70 Theoretical pI: 7.36
Amino acid composition: 
Ala (A) 26 3.2% Arg (R) 42 5.2% Asn (N) 51 6.3% Asp (D) 49 6.1% Cys (C) 18 2.2% Gln (Q) 38 4.7% Glu (E) 41 5.1% Gly (G) 32 4.0% His (H) 30 3.7% Ile (I) 55 6.8% Leu (L) 96 11.9% Lys (K) 48 5.9% Met (M) 8 1.0% Phe (F) 35 4.3% Pro (P) 40 5.0% Ser (S) 75 9.3% Thr (T) 48 5.9% Trp (W) 11 1.4% Tyr (Y) 34 4.2% Val (V) 30 3.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 90 Total number of positively charged residues (Arg + Lys): 90 Atomic composition: Carbon C 4166 Hydrogen H 6475 Nitrogen N 1141 Oxygen O 1234 Sulfur S 26 Formula: C4166H6475N1141O1234S26 Total number of atoms: 13042 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 112285 Abs 0.1% (=1 g/l) 1.206, assuming all pairs of Cys residues form cystines Ext. coefficient 111160 Abs 0.1% (=1 g/l) 1.194, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.83 This classifies the protein as unstable. Aliphatic index: 86.98 Grand average of hydropathicity (GRAVY): -0.471