ProtParam
User-provided sequence:
10 20 30 40 50 60
MPDLKSKTLS SQSLGAAIPP EIVYQILTYQ FRDLLRNDHP GTAEKFNENL TTFVKSNLTV
70 80 90 100 110 120
NKTFSHICQV LIYRYCNLTT AKRFHGLLQT LKGNRCLCNK IEVADFQELT SIGLGRSSEM
130 140 150 160 170 180
NKMIKNLTNE TLLEFLMLTK ANLREFLACE NIQDDLDDNI IKYILSPGKV LSVVDFCGCS
190 200 210 220 230 240
GTTFTESFIK ALDKYYPNKS IDQYRLEPIQ QNYQITCLGL NDCIDLPSHV LWKILKMLPE
250 260 270 280 290 300
LQKLDLSHTS IDDSTLYHGI PHWKNLTHLS LATCLQVTPR AVLEFFSHHP TITDPDNTST
310 320 330 340 350 360
LEWLNVSVIA HSSSWNEVHT MFLLKKLCQH GHNKTLQYLN IGGLPLHVAP SFGEDPISES
370 380 390 400 410 420
TYYYQCRDSL QFIKWNFPKL KSLSIKGNSI PISTLVEFLT PIDQDHPNCA QKLKFLNISG
430 440 450 460 470 480
NSYVNKWTIQ DSLLYTCSPS LVALEVSFDS WQQIEKLNDR HEIIAYRYKN PNSVIKDIST
490 500 510 520 530 540
AEQVKWKCYI DSSYGRRYWL YKTDPFLNRD DLDSKSNLTR YDFEGHKIIE IINQPDFLKF
550 560 570 580 590 600
AQSKIMLGCG LVPQSGIRRK LCYRDLKPPV SQFLNRKGAI SLGDTPLPII TPTLPRGGWR
610 620 630 640 650 660
IIHNEDDNNS HVEDSQNHVN AIPRRNSLLS RPTLRSNNGS SSANPFAINV SPASQIRDGL
670 680 690 700 710 720
YWDRSVHDLR ELSLQEQRIQ ELADEQQELR TIANFEETDD EYLHDPDLQR RRSQLHLFES
730 740 750 760 770 780
SRSRSGNKTR PSLTGEHSSS ASFLSFSHFN HLHKRKNYYF THPDEFVYDP KDPLTTQRYR
790 800
LHFEIVNEYQ VFGCIERGMY RYYSLKA
References and
documentation are available.
Number of amino acids: 807
Molecular weight: 93122.70
Theoretical pI: 7.36
Total number of negatively charged residues (Asp + Glu): 90
Total number of positively charged residues (Arg + Lys): 90
Atomic composition:
Carbon C 4166
Hydrogen H 6475
Nitrogen N 1141
Oxygen O 1234
Sulfur S 26
Formula: C
4166H
6475N
1141O
1234S
26
Total number of atoms: 13042
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 112285
Abs 0.1% (=1 g/l) 1.206, assuming all pairs of Cys residues form cystines
Ext. coefficient 111160
Abs 0.1% (=1 g/l) 1.194, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 45.83
This classifies the protein as unstable.
Aliphatic index: 86.98
Grand average of hydropathicity (GRAVY): -0.471