ProtParam
User-provided sequence:
10 20 30 40 50 60
MPGQIISIPF LSQNEDMDKY LLEYRSLKLL HQSSNSFQSH NAPSHQSNYH PHYNHMKYNN
70 80 90 100 110 120
TGSYYYYNNN NNSSVNPHNQ AGLQSINRSI PSAPYGAYNQ NRANDVPYMN TQKKHHRFSA
130 140 150 160 170 180
NNNLNQQKYK QYPQYTSNPM VTAHLKQTYP QLYYNSNVNA HNNNNNSNNN NNNNNNSNNN
190 200 210 220 230 240
NNLYNQTQFS TRYFNSNSSP SLTSSTSNSS SPYNQSTFEY ILPSTSAAST NLSSSSSNNS
250 260 270 280 290 300
MHTNPTTATS TSADLINDLP VGPTSSSLIS DLHSPPTVSF LPASQTLLMS STTSSSIGTN
310 320 330 340 350 360
INPPQHSPSP SQREDFSTAP VNMSSSASLL MNDSSLGWGS NHMNVSSSSQ PASSRPFGIW
NTDMSVWS
References and
documentation are available.
Number of amino acids: 368
Molecular weight: 40766.80
Theoretical pI: 8.57
Total number of negatively charged residues (Asp + Glu): 13
Total number of positively charged residues (Arg + Lys): 15
Atomic composition:
Carbon C 1743
Hydrogen H 2629
Nitrogen N 515
Oxygen O 601
Sulfur S 11
Formula: C
1743H
2629N
515O
601S
11
Total number of atoms: 5499
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 49280
Abs 0.1% (=1 g/l) 1.209
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 62.49
This classifies the protein as unstable.
Aliphatic index: 48.53
Grand average of hydropathicity (GRAVY): -0.965