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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPGVSVRDVA AQDFINAYAS FLQRQGKLEV PGYVDIVKTS SGNEMPPQDA EGWFYKRAAS

70 80 90 100 110 120
VARHIYMRKQ VGVGKLNKLY GGAKSRGVRP YKHIDASGSI NRKVLQALEK IGIVEISPKG

130 140
GRRISENGQR DLDRIAAQTL EEDE


References and documentation are available.

Number of amino acids: 144 Molecular weight: 15917.11 Theoretical pI: 9.61
Amino acid composition: 
Ala (A) 13 9.0% Arg (R) 12 8.3% Asn (N) 5 3.5% Asp (D) 8 5.6% Cys (C) 0 0.0% Gln (Q) 8 5.6% Glu (E) 9 6.2% Gly (G) 15 10.4% His (H) 2 1.4% Ile (I) 10 6.9% Leu (L) 8 5.6% Lys (K) 11 7.6% Met (M) 3 2.1% Phe (F) 3 2.1% Pro (P) 6 4.2% Ser (S) 10 6.9% Thr (T) 2 1.4% Trp (W) 1 0.7% Tyr (Y) 6 4.2% Val (V) 12 8.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 17 Total number of positively charged residues (Arg + Lys): 23 Atomic composition: Carbon C 699 Hydrogen H 1129 Nitrogen N 209 Oxygen O 210 Sulfur S 3 Formula: C699H1129N209O210S3 Total number of atoms: 2250 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 14440 Abs 0.1% (=1 g/l) 0.907 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 53.43 This classifies the protein as unstable. Aliphatic index: 81.94 Grand average of hydropathicity (GRAVY): -0.547