ProtParam
User-provided sequence:
10 20 30 40 50 60
MPGVSVRDVA AQDFINAYAS FLQRQGKLEV PGYVDIVKTS SGNEMPPQDA EGWFYKRAAS
70 80 90 100 110 120
VARHIYMRKQ VGVGKLNKLY GGAKSRGVRP YKHIDASGSI NRKVLQALEK IGIVEISPKG
130 140
GRRISENGQR DLDRIAAQTL EEDE
References and
documentation are available.
Number of amino acids: 144
Molecular weight: 15917.11
Theoretical pI: 9.61
Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 23
Atomic composition:
Carbon C 699
Hydrogen H 1129
Nitrogen N 209
Oxygen O 210
Sulfur S 3
Formula: C
699H
1129N
209O
210S
3
Total number of atoms: 2250
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 14440
Abs 0.1% (=1 g/l) 0.907
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 53.43
This classifies the protein as unstable.
Aliphatic index: 81.94
Grand average of hydropathicity (GRAVY): -0.547