ProtParam
User-provided sequence:
10 20 30 40 50 60
MPKLVLVRHG QSEWNEKNLF TGWVDVKLSA KGQQEAARAG ELLKEKKVYP DVLYTSKLSR
70 80 90 100 110 120
AIQTANIALE KADRLWIPVN RSWRLNERHY GDLQGKDKAE TLKKFGEEKF NTYRRSFDVP
130 140 150 160 170 180
PPPIDASSPF SQKGDERYKY VDPNVLPETE SLALVIDRLL PYWQDVIAKD LLSGKTVMIA
190 200 210 220 230 240
AHGNSLRGLV KHLEGISDAD IAKLNIPTGI PLVFELDENL KPSKPSYYLD PEAAAAGAAA
VANQGKK
References and
documentation are available.
Number of amino acids: 247
Molecular weight: 27608.56
Theoretical pI: 8.81
Total number of negatively charged residues (Asp + Glu): 33
Total number of positively charged residues (Arg + Lys): 36
Atomic composition:
Carbon C 1246
Hydrogen H 1975
Nitrogen N 339
Oxygen O 365
Sulfur S 2
Formula: C
1246H
1975N
339O
365S
2
Total number of atoms: 3927
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 40910
Abs 0.1% (=1 g/l) 1.482
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 34.14
This classifies the protein as stable.
Aliphatic index: 90.08
Grand average of hydropathicity (GRAVY): -0.489