ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPLQSLVKAL WNVLHEEESE GYPDLTELIA EVESYQQRYP KQNPTNSQKI RHILDEIYEK 

        70         80         90        100        110        120 
TPFNNTRRRI LWLAVLKTVI PLLILDRQAV GEWWDQIFFP FLNSPTQLKP VFSDLKSILF 

       130        140        150        160        170        180 
YILIFHDEDE WGGDLRRECA EETITRLVDL YVSKAIENLG DVESQEQRNQ TIECLVNVLV 

       190        200        210        220        230        240 
HYGIQRPKEL SSCFCHHFLN PPTRIPILSV MVEVIRRQGP RLYEIPQTGF YDLVLKCAEF 

       250        260        270        280        290        300 
DTSPILLSYA LSFILMILSH ICNSLDDSLY RLFCIYLRFS MIDPTSGFPS STASGNWEVF 

       310        320        330        340        350        360 
HDFMSTYAST TTSQTDSSYN DVHDIVGSSQ PDYLESLDYS QLFSILYALY PINFLEFLRD 

       370        380        390        400        410        420 
PKLYASKHNF QIRYSFNQEL LSTKSDGLLG RHLAHSNFLK YTAETELTDK SRWTRLDSIA 

       430        440        450        460        470        480 
VVALCNSLNA VGIAESVMDP FGGKLPTTYE ETSSATGLLA YPNESHDIAS EPFSISWPQN 

       490        500        510        520        530        540 
PSISGSVHSA TTFDKAQLSN TEDSYDNISH GTSYSEGVSS IHMVKGERGS NNLELTSESL 

       550        560        570        580        590        600 
SSTNDTIRRL QRDLLFLQNE LRFEKFVRQQ HLQNIGKLHR EHILDMAVES ERQKLLLTNK 

       610        620        630        640        650        660 
RYKAQIELLN SEIDKHRSES QAALNRRVKW ENDFNNKIKA LREEKKAWKS EESELKSSIE 

       670        680        690        700        710        720 
SLISQLESIR NSQIDIAFSK NQLELKLQLY ETKLKEYEQH LSCVNISKKQ VSSSSDTSFG 

       730        740        750        760        770        780 
NTKMDSSMIL SNSEAVSDEQ ERELIESEKH RMKLESENLH LQANIELLKK DLEAINVVYE 

       790        800        810        820        830        840 
AKIFDLEKRL SSEANAPELH NPVNLNYDAQ LSKISEIKEN YDELLTRYRE LEGKFLESQA 

       850        860        870        880        890 
EVEELKNFQK PLVDTGSSIH SSPGLQQSKF IIRNDSLHPK VGPPRRQSTD TSRSTFRQY 

References and documentation are available.

Number of amino acids: 899

Molecular weight: 103435.46

Theoretical pI: 5.39

Amino acid composition: 
Ala (A)  38	  4.2%
Arg (R)  46	  5.1%
Asn (N)  49	  5.5%
Asp (D)  46	  5.1%
Cys (C)   9	  1.0%
Gln (Q)  44	  4.9%
Glu (E)  82	  9.1%
Gly (G)  28	  3.1%
His (H)  26	  2.9%
Ile (I)  58	  6.5%
Leu (L) 109	 12.1%
Lys (K)  51	  5.7%
Met (M)  11	  1.2%
Phe (F)  37	  4.1%
Pro (P)  34	  3.8%
Ser (S) 105	 11.7%
Thr (T)  44	  4.9%
Trp (W)  10	  1.1%
Tyr (Y)  33	  3.7%
Val (V)  39	  4.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 128
Total number of positively charged residues (Arg + Lys): 97

Atomic composition:

Carbon      C	      4598
Hydrogen    H	      7205
Nitrogen    N	      1243
Oxygen      O	      1431
Sulfur      S	        20

Formula: C4598H7205N1243O1431S20
Total number of atoms: 14497

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   104670
Abs 0.1% (=1 g/l)   1.012, assuming all pairs of Cys residues form cystines


Ext. coefficient   104170
Abs 0.1% (=1 g/l)   1.007, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 57.89
This classifies the protein as unstable.



Aliphatic index: 89.25

Grand average of hydropathicity (GRAVY): -0.490