ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPLRLDIKRK FAQRSERVKS VDLHPTEPWI LASLYSGTVC IWNYQTQTIT KSFEVTELPV 

        70         80         90        100        110        120 
RSAKFIPRKQ WVVAGADDMY IRVYNYNTMD KVKVFEAHSD YIRCVAVHPT LPYVLSSSDD 

       130        140        150        160        170        180 
MLIKLWDWEN GWACTQIFEG HSHYVMQVVF NPKDTNTFAS ASLDRTIKIW NLGSPDPNFT 

       190        200        210        220        230        240 
LDAHQKGVNC VDYFTGGDKP YLITGSDDHT AKVWDYQTKS CVQTLDGHTH NVSAVCFHPE 

       250        260        270        280        290        300 
LPIIITGSED GTVRIWHATT YRLENTLNYG LERVWAIGYI KSSRRVVIGY DEGTIMVKLG 

       310        320        330        340        350        360 
REIPVASMDS SGKIIWAKHN EIQTANIKSI GAGYEATDGE RLPLSVKELG TCDLYPQSLK 

       370        380        390        400        410        420 
HNPNGRFVVV CGDGEYIIYT ALAWRNRSFG SGLEFVWSSE GECAVRESSS KIKIFSKNFQ 

       430        440        450        460        470        480 
ERKSIRPTFS AEKIFGGTLL AMCSNDFICF YDWAECRLIQ QIDVTVKNLY WAESGDLVAI 

       490        500        510        520        530        540 
ASDTSFYILK YNRELVSSHF DSGRPTDEEG VEDAFEVLHE NDERVRTGIW VGDCFIYNNS 

       550        560        570        580        590        600 
SWKLNYCVGG EVTTMYHLDR PMYLLGYIAN QSRVYLVDKE FNVIGYTLLL SLIEYKTLVM 

       610        620        630        640        650        660 
RGDLDRANQI LPTIPKEQHN NVAHFLESRG MIEDALEIAT DPDYKFDLAI QLGRLEIAKE 

       670        680        690        700        710        720 
IAEEVQSESK WKQLGELAMS SGKLQLAEDC MKYAMDLSGL LLLYSSLGDA EGVSKLACLA 

       730        740        750        760        770        780 
KEQGKNNVAF LCLFTLGRLE DCLQLLVESN RIPEAALMAR SYLPSKVSEI VALWREDLSK 

       790        800        810        820        830        840 
VNPKAAESLA DPEEYSNLFE DWQVALSVEA NTAETRGVYT AAENYPSHAD KPSITLVEAF 

       850        860        870        880        890        900 
RNLQVEAEES LENGNIDHEV AEENGHVENE GDEEEQQEEE VNEEEGVVDA DSTDGAVLVN 


GSEVLTPHP 

References and documentation are available.

Number of amino acids: 909

Molecular weight: 102476.44

Theoretical pI: 4.84

Amino acid composition: 
Ala (A)  63	  6.9%
Arg (R)  39	  4.3%
Asn (N)  44	  4.8%
Asp (D)  56	  6.2%
Cys (C)  18	  2.0%
Gln (Q)  27	  3.0%
Glu (E)  81	  8.9%
Gly (G)  56	  6.2%
His (H)  22	  2.4%
Ile (I)  53	  5.8%
Leu (L)  83	  9.1%
Lys (K)  46	  5.1%
Met (M)  16	  1.8%
Phe (F)  30	  3.3%
Pro (P)  31	  3.4%
Ser (S)  69	  7.6%
Thr (T)  48	  5.3%
Trp (W)  20	  2.2%
Tyr (Y)  38	  4.2%
Val (V)  69	  7.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 137
Total number of positively charged residues (Arg + Lys): 85

Atomic composition:

Carbon      C	      4564
Hydrogen    H	      7047
Nitrogen    N	      1207
Oxygen      O	      1410
Sulfur      S	        34

Formula: C4564H7047N1207O1410S34
Total number of atoms: 14262

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   167745
Abs 0.1% (=1 g/l)   1.637, assuming all pairs of Cys residues form cystines


Ext. coefficient   166620
Abs 0.1% (=1 g/l)   1.626, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.57
This classifies the protein as stable.



Aliphatic index: 87.29

Grand average of hydropathicity (GRAVY): -0.292