ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPNVLPRQES FVTRVTGQKW TKYHVRVFIH TFIIYVLIHA ARKTLSTVKP SLINVWTDNS 

        70         80         90        100        110        120 
SSPDGPLFDS EQSATEFLGA LDTGFMITYS IGLYICGTLG DHYNPRRILA LGMALSAISV 

       130        140        150        160        170        180 
FTFGFVTEVS HFYSAPLYAV LWISNGFFQS VGWPLEVCIM GNWFGKTARG AVIGAWSTNA 

       190        200        210        220        230        240 
SVGNILATLI ASWTVNIGYQ YPFLIISTAL FTYSIIIFFN LPSAPWEVKQ QIEGSDIKEI 

       250        260        270        280        290        300 
PSDDNERPPP LGFFRAWLLP GVLAFAISYL CLKLVNDGFF FWLPFYLHNG LNWKESTADG 

       310        320        330        340        350        360 
LAAWYDVGGI ISSIIAGALS DRMKSRTILV FTMLLFSTVT LFAYAHSPIS YYWNAFILLI 

       370        380        390        400        410        420 
VGFFIGGPLN MIAGCITSDL GRSEMLRGNA EALSTVTGII DGTGSVGSAI GQWLIPLVRN 

       430        440        450        460        470 
WLGWDAIFYG FMIMVVCSAL CISPVIWREW KENKHEKISQ KTDDQTCHNV EMNKC 

References and documentation are available.

Number of amino acids: 475

Molecular weight: 52889.31

Theoretical pI: 6.31

Amino acid composition: 
Ala (A)  34	  7.2%
Arg (R)  15	  3.2%
Asn (N)  21	  4.4%
Asp (D)  17	  3.6%
Cys (C)   8	  1.7%
Gln (Q)  10	  2.1%
Glu (E)  16	  3.4%
Gly (G)  39	  8.2%
His (H)   9	  1.9%
Ile (I)  45	  9.5%
Leu (L)  46	  9.7%
Lys (K)  15	  3.2%
Met (M)  11	  2.3%
Phe (F)  32	  6.7%
Pro (P)  21	  4.4%
Ser (S)  40	  8.4%
Thr (T)  30	  6.3%
Trp (W)  18	  3.8%
Tyr (Y)  17	  3.6%
Val (V)  31	  6.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 33
Total number of positively charged residues (Arg + Lys): 30

Atomic composition:

Carbon      C	      2460
Hydrogen    H	      3712
Nitrogen    N	       602
Oxygen      O	       660
Sulfur      S	        19

Formula: C2460H3712N602O660S19
Total number of atoms: 7453

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   124830
Abs 0.1% (=1 g/l)   2.360, assuming all pairs of Cys residues form cystines


Ext. coefficient   124330
Abs 0.1% (=1 g/l)   2.351, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.23
This classifies the protein as stable.



Aliphatic index: 100.80

Grand average of hydropathicity (GRAVY): 0.379