ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPPASTSTTN DMITEEPTSP HQIPRLTRRL TGFLPQEIKS IDTMIPLKSR ALWNKHQVKK 

        70         80         90        100        110        120 
FNKAEDFQDR FIDHVETTLA RSLYNCDDMA AYEAASMSIR DNLVIDWNKT QQKFTTRDPK 

       130        140        150        160        170        180 
RVYYLSLEFL MGRALDNALI NMKIEDPEDP AASKGKPREM IKGALDDLGF KLEDVLDQEP 

       190        200        210        220        230        240 
DAGLGNGGLG RLAACFVDSM ATEGIPAWGY GLRYEYGIFA QKIIDGYQVE TPDYWLNSGN 

       250        260        270        280        290        300 
PWEIERNEVQ IPVTFYGYVD RPEGGKTTLS ASQWIGGERV LAVAYDFPVP GFKTSNVNNL 

       310        320        330        340        350        360 
RLWQARPTTE FDFAKFNNGD YKNSVAQQQR AESITAVLYP NDNFAQGKEL RLKQQYFWCA 

       370        380        390        400        410        420 
ASLHDILRRF KKSKRPWTEF PDQVAIQLND THPTLAIVEL QRVLVDLEKL DWHEAWDIVT 

       430        440        450        460        470        480 
KTFAYTNHTV MQEALEKWPV GLFGHLLPRH LEIIYDINWF FLQDVAKKFP KDVDLLSRIS 

       490        500        510        520        530        540 
IIEENSPERQ IRMAFLAIVG SHKVNGVAEL HSELIKTTIF KDFVKFYGPS KFVNVTNGIT 

       550        560        570        580        590        600 
PRRWLKQANP SLAKLISETL NDPTEEYLLD MAKLTQLGKY VEDKEFLKKW NQVKLNNKIR 

       610        620        630        640        650        660 
LVDLIKKEND GVDIINREYL DDTLFDMQVK RIHEYKRQQL NVFGIIYRYL AMKNMLKNGA 

       670        680        690        700        710        720 
SIEEVAKKYP RKVSIFGGKS APGYYMAKLI IKLINCVADI VNNDESIEHL LKVVFVADYN 

       730        740        750        760        770        780 
VSKAEIIIPA SDLSEHISTA GTEASGTSNM KFVMNGGLII GTVDGANVEI TREIGEDNVF 

       790        800        810        820        830        840 
LFGNLSENVE ELRYNHQYHP QDLPSSLDSV LSYIESGQFS PENPNEFKPL VDSIKYHGDY 

       850        860        870        880        890        900 
YLVSDDFESY LATHELVDQE FHNQRSEWLK KSVLSVANVG FFSSDRCIEE YSDTIWNVEP 


VT 

References and documentation are available.

Number of amino acids: 902

Molecular weight: 103275.32

Theoretical pI: 5.41

Amino acid composition: 
Ala (A)  56	  6.2%
Arg (R)  40	  4.4%
Asn (N)  53	  5.9%
Asp (D)  61	  6.8%
Cys (C)   5	  0.6%
Gln (Q)  35	  3.9%
Glu (E)  66	  7.3%
Gly (G)  48	  5.3%
His (H)  19	  2.1%
Ile (I)  61	  6.8%
Leu (L)  83	  9.2%
Lys (K)  63	  7.0%
Met (M)  18	  2.0%
Phe (F)  43	  4.8%
Pro (P)  41	  4.5%
Ser (S)  53	  5.9%
Thr (T)  45	  5.0%
Trp (W)  17	  1.9%
Tyr (Y)  36	  4.0%
Val (V)  59	  6.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 127
Total number of positively charged residues (Arg + Lys): 103

Atomic composition:

Carbon      C	      4663
Hydrogen    H	      7210
Nitrogen    N	      1228
Oxygen      O	      1379
Sulfur      S	        23

Formula: C4663H7210N1228O1379S23
Total number of atoms: 14503

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   147390
Abs 0.1% (=1 g/l)   1.427, assuming all pairs of Cys residues form cystines


Ext. coefficient   147140
Abs 0.1% (=1 g/l)   1.425, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.82
This classifies the protein as stable.



Aliphatic index: 87.44

Grand average of hydropathicity (GRAVY): -0.393