ProtParam
User-provided sequence:
10 20 30 40 50 60
MPPLDKRIKK FLKDSIRIAP KISGKGELSE LRTGLVSQYP QTRKDAIKKT IQQMTLGKDV
70 80 90 100 110 120
SSLFPDVLKN IATIDVEQKK LVYLYVMNYA ETHPELCILA VNTFITDAQD PNPLIRCMAI
130 140 150 160 170 180
RTMSMIRVDK ILEYIETPLR RTLHDDNAYV RKTAVICVAK LFQLNKDLCV ELGVVEDLVN
190 200 210 220 230 240
ALDDSNPLVI ANATAALIEI HNMDMDAVDL SSLIQSHVSQ FLLALNECTE WARIIILGTL
250 260 270 280 290 300
SEYSAKDSLE AQDIIDRVTA HLQHVNPAVV LATIKVIVRN LPQIEYSSNS LIMKRLSSAF
310 320 330 340 350 360
VSLMSTPPEM QYVALKNIRI ILEKYPELLT KELRIFYVKF NDPLYVKLEK IDILVRLVDP
370 380 390 400 410 420
SNLKQCTLLL TELKEYAMEY EPEFVSRAIQ ALSQLGIKYA QESFVSKVLD ILLELLERQD
430 440 450 460 470 480
TIKDDCCISL CDLLRHCPGN DKMAKQVCAV FNTWSNPEVL LQSDIAKCNY VWLLGQHPNN
490 500 510 520 530 540
FSDLESKINI FIENFVQEEA LTQMSLLMTI VRLHATLTGS MLQSVLELAT QQTHELDVRD
550 560 570 580 590 600
MAMMYWRCLS MPNNESLVND LCQNKLPMIS NTLEKFSPEV LEKLLMELGT ISSIYFKPDS
610 620 630 640 650 660
NRRKGKKYVQ NIVKGKHIEE LESMAKNEIS SKANDDVLLD FDERDDVTNT NAGMLNTLTT
670 680 690 700 710 720
LGDLDDLFDF GPSEDATQIN TNDTKAVQGL KELKLGGDSN GISSGGKNNP DVSGGNIVSQ
DLLDLF
References and
documentation are available.
Number of amino acids: 726
Molecular weight: 81868.73
Theoretical pI: 5.09
Total number of negatively charged residues (Asp + Glu): 99
Total number of positively charged residues (Arg + Lys): 76
Atomic composition:
Carbon C 3632
Hydrogen H 5890
Nitrogen N 954
Oxygen O 1108
Sulfur S 38
Formula: C
3632H
5890N
954O
1108S
38
Total number of atoms: 11622
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 51185
Abs 0.1% (=1 g/l) 0.625, assuming all pairs of Cys residues form cystines
Ext. coefficient 50310
Abs 0.1% (=1 g/l) 0.615, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 41.39
This classifies the protein as unstable.
Aliphatic index: 107.81
Grand average of hydropathicity (GRAVY): -0.086