ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPPLFKGLKQ MAKPIAYVSR FSAKRPIHII LFSLIISAFA YLSVIQYYFN GWQLDSNSVF 

        70         80         90        100        110        120 
ETAPNKDSNT LFQECSHYYR DSSLDGWVSI TAHEASELPA PHHYYLLNLN FNSPNETDSI 

       130        140        150        160        170        180 
PELANTVFEK DNTKYILQED LSVSKEISST DGTKWRLRSD RKSLFDVKTL AYSLYDVFSE 

       190        200        210        220        230        240 
NVTQADPFDV LIMVTAYLMM FYTIFGLFND MRKTGSNFWL SASTVVNSAS SLFLALYVTQ 

       250        260        270        280        290        300 
CILGKEVSAL TLFEGLPFIV VVVGFKHKIK IAQYALEKFE RVGLSKRITT DEIVFESVSE 

       310        320        330        340        350        360 
EGGRLIQDHL LCIFAFIGCS MYAHQLKTLT NFCILSAFIL IFELILTPTF YSAILALRLE 

       370        380        390        400        410        420 
MNVIHRSTII KQTLEEDGVV PSTARIISKA EKKSVSSFLN LSVVVIIMKL SVILLFVFIN 

       430        440        450        460        470        480 
FYNFGANWVN DAFNSLYFDK ERVSLPDFIT SNASENFKEQ AIVSVTPLLY YKPIKSYQRI 

       490        500        510        520        530        540 
EDMVLLLLRN VSVAIRDRFV SKLVLSALVC SAVINVYLLN AARIHTSYTA DQLVKTEVTK 

       550        560        570        580        590        600 
KSFTAPVQKA STPVLTNKTV ISGSKVKSLS SAQSSSSGPS SSSEEDDSRD IESLDKKIRP 

       610        620        630        640        650        660 
LEELEALLSS GNTKQLKNKE VAALVIHGKL PLYALEKKLG DTTRAVAVRR KALSILAEAP 

       670        680        690        700        710        720 
VLASDRLPYK NYDYDRVFGA CCENVIGYMP LPVGVIGPLV IDGTSYHIPM ATTEGCLVAS 

       730        740        750        760        770        780 
AMRGCKAINA GGGATTVLTK DGMTRGPVVR FPTLKRSGAC KIWLDSEEGQ NAIKKAFNST 

       790        800        810        820        830        840 
SRFARLQHIQ TCLAGDLLFM RFRTTTGDAM GMNMISKGVE YSLKQMVEEY GWEDMEVVSV 

       850        860        870        880        890        900 
SGNYCTDKKP AAINWIEGRG KSVVAEATIP GDVVRKVLKS DVSALVELNI AKNLVGSAMA 

       910        920        930        940        950        960 
GSVGGFNAHA ANLVTAVFLA LGQDPAQNVE SSNCITLMKE VDGDLRISVS MPSIEVGTIG 

       970        980        990       1000       1010       1020 
GGTVLEPQGA MLDLLGVRGP HATAPGTNAR QLARIVACAV LAGELSLCAA LAAGHLVQSH 

      1030       1040       1050 
MTHNRKPAEP TKPNNLDATD INRLKDGSVT CIKS 

References and documentation are available.

Number of amino acids: 1054

Molecular weight: 115625.59

Theoretical pI: 8.24

Amino acid composition: 
Ala (A)  90	  8.5%
Arg (R)  42	  4.0%
Asn (N)  49	  4.6%
Asp (D)  47	  4.5%
Cys (C)  17	  1.6%
Gln (Q)  26	  2.5%
Glu (E)  55	  5.2%
Gly (G)  60	  5.7%
His (H)  18	  1.7%
Ile (I)  68	  6.5%
Leu (L) 113	 10.7%
Lys (K)  65	  6.2%
Met (M)  25	  2.4%
Phe (F)  47	  4.5%
Pro (P)  39	  3.7%
Ser (S) 100	  9.5%
Thr (T)  63	  6.0%
Trp (W)   8	  0.8%
Tyr (Y)  33	  3.1%
Val (V)  89	  8.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 102
Total number of positively charged residues (Arg + Lys): 107

Atomic composition:

Carbon      C	      5191
Hydrogen    H	      8280
Nitrogen    N	      1364
Oxygen      O	      1530
Sulfur      S	        42

Formula: C5191H8280N1364O1530S42
Total number of atoms: 16407

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    94170
Abs 0.1% (=1 g/l)   0.814, assuming all pairs of Cys residues form cystines


Ext. coefficient    93170
Abs 0.1% (=1 g/l)   0.806, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.44
This classifies the protein as stable.



Aliphatic index: 100.00

Grand average of hydropathicity (GRAVY): 0.107