ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPPSKGLNGK LEKPKHALQA IVLSDSYNYR FRPLTLDKPR CLLPLANTPL IEYTFEFLAL 

        70         80         90        100        110        120 
AGVQEVYVFC CAHAGQIREY IEKSKWNLPS SPFSVNTIVS RESLSVGDAL RELDSKQLIT 

       130        140        150        160        170        180 
SDFILVSGDV VSNVPLNEVL KEHRKRREDD KNAIMTMVVR EASPFHRTRA RTESSVFVID 

       190        200        210        220        230        240 
KKTSQCVHYQ ANERGKHYVS MDPEIFNEHE ELEVRNDLID CQIDICSNDV PALFTENFDY 

       250        260        270        280        290        300 
QDIRKDFVYG VLTSDLLGKK IHCHVAKENY AARVRSLQTY DAISKDVLSR WVYPFVPDSN 

       310        320        330        340        350        360 
LLNQTFSYQR HQIYKEEDVV LARSCIIKAR TLIGAYTKVG DASVVANTII GRNCTIGSNC 

       370        380        390        400        410        420 
SIDSAFLWED VVIGDNCRIG KAILANSVKI GNNCSIEDGA IVAAGVVIGD NTIIEKNKRL 

       430        440        450        460        470        480 
TTFESHSQGT LNDPSLVGIG GRGQEYHAEE DSDDEGEFME ASGLIESTNE LHLSDSESSE 

       490        500        510        520        530        540 
TSSSSEEDME FIPFSARRDS ANTINSEDFD EGDFNKEAQQ SLERAFEENH QIDIAALELN 

       550        560        570        580        590        600 
TLRMAMNANY HEVRSAIVLA LLRRIMHLDV SPKEALAKVM TRWGPLLAKL TFSHEEQVDN 

       610        620        630        640        650        660 
VLTLQKYCVR LSMTRHFLQL LGYFYQLEIA EENAIQEWYS DPRSSEGELA ALRDAGGKQF 

       670 
VDWLNTAESE SESEEGSE 

References and documentation are available.

Number of amino acids: 678

Molecular weight: 76325.64

Theoretical pI: 4.94

Amino acid composition: 
Ala (A)  49	  7.2%
Arg (R)  38	  5.6%
Asn (N)  37	  5.5%
Asp (D)  44	  6.5%
Cys (C)  13	  1.9%
Gln (Q)  23	  3.4%
Glu (E)  63	  9.3%
Gly (G)  33	  4.9%
His (H)  18	  2.7%
Ile (I)  43	  6.3%
Leu (L)  62	  9.1%
Lys (K)  32	  4.7%
Met (M)  11	  1.6%
Phe (F)  26	  3.8%
Pro (P)  20	  2.9%
Ser (S)  62	  9.1%
Thr (T)  30	  4.4%
Trp (W)   6	  0.9%
Tyr (Y)  21	  3.1%
Val (V)  47	  6.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 107
Total number of positively charged residues (Arg + Lys): 70

Atomic composition:

Carbon      C	      3349
Hydrogen    H	      5264
Nitrogen    N	       926
Oxygen      O	      1066
Sulfur      S	        24

Formula: C3349H5264N926O1066S24
Total number of atoms: 10629

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    65040
Abs 0.1% (=1 g/l)   0.852, assuming all pairs of Cys residues form cystines


Ext. coefficient    64290
Abs 0.1% (=1 g/l)   0.842, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 51.13
This classifies the protein as unstable.



Aliphatic index: 87.73

Grand average of hydropathicity (GRAVY): -0.362