ProtParam
User-provided sequence:
10 20 30 40 50 60
MPPYISAFQA AYIGIEVLIA LVSVPGNVLV IWAVKVNQAL RDATFCFIVS LAVADVAVGA
70 80 90 100 110 120
LVIPLAILIN IGPQTYFHTC LMVACPVLIL TQSSILALLA IAVDRYLRVK IPLRYKTVVT
130 140 150 160 170 180
QRRAAVAIAG CWILSLVVGL TPMFGWNNLS VVEQDWRANG SVGEPVIKCE FEKVISMEYM
190 200 210 220 230 240
VYFNFFVWVL PPLLLMVLIY LEVFYLIRKQ LNKKVSASSG DPQKYYGKEL KIAKSLALIL
250 260 270 280 290 300
FLFALSWLPL HILNCITLFC PTCQKTSILI YIAIFLTHGN SAMNPIVYAF RIHKFRVTFL
310 320
KIWNDHFRCQ PKPPIDEDLP EEKAED
References and
documentation are available.
Number of amino acids: 326
Molecular weight: 36698.98
Theoretical pI: 8.88
Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 28
Atomic composition:
Carbon C 1726
Hydrogen H 2709
Nitrogen N 415
Oxygen O 432
Sulfur S 16
Formula: C
1726H
2709N
415O
432S
16
Total number of atoms: 5298
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 58370
Abs 0.1% (=1 g/l) 1.591, assuming all pairs of Cys residues form cystines
Ext. coefficient 57870
Abs 0.1% (=1 g/l) 1.577, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 36.76
This classifies the protein as stable.
Aliphatic index: 127.67
Grand average of hydropathicity (GRAVY): 0.684