ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPQLENNEPL LINEEEEEET AYDETEKVHI VRNEEEDDLE HGVGCGGAPP FSWKKLWLFT 

        70         80         90        100        110        120 
GPGFLMSIAF LDPGNLEGDL QAGAVAGYSL LWLLMWATAM GLLVQLLSAR LGVATGRHLA 

       130        140        150        160        170        180 
ELCRDEYPTW ARMVLWVMAE LALIGSDIQE VIGSAIAIKI LSNGILPLWA GVVITALDCF 

       190        200        210        220        230        240 
VFLFLENYGI RKLEAVFAVL IATMGVSFAW MFGQAKPSGS ELLIGILVPK LSSRTIQKAV 

       250        260        270        280        290        300 
GVVGCIIMPH NVFLHSALVQ SREVDKRQKY RVQEALNYYT IESTIALFIS FLINLFVTTV 

       310        320        330        340        350        360 
FAKGFYNTDL ANSIGLVNAG QYLQEKYGGG VFPILYIWAI GLLAAGQSST ITGTYAGQFI 

       370        380        390        400        410        420 
MGGFLNFKMK KWLRALITRS CAIIPTIIVA LVFDSSEATL DVLNEWLNVL QSIQIPFALI 

       430        440        450        460        470        480 
PLLCLVSKEQ IMGSFKIGPL YKTIAWLVAA LVIMINGYLL LEFFSNEVSG IVYTGFVTLF 

       490        500 
TASYGAFILY LIARGITFTP WPFKAESSH 

References and documentation are available.

Number of amino acids: 509

Molecular weight: 56137.84

Theoretical pI: 5.11

Amino acid composition: 
Ala (A)  46	  9.0%
Arg (R)  13	  2.6%
Asn (N)  18	  3.5%
Asp (D)  12	  2.4%
Cys (C)   6	  1.2%
Gln (Q)  16	  3.1%
Glu (E)  32	  6.3%
Gly (G)  43	  8.4%
His (H)   6	  1.2%
Ile (I)  45	  8.8%
Leu (L)  69	 13.6%
Lys (K)  19	  3.7%
Met (M)  13	  2.6%
Phe (F)  30	  5.9%
Pro (P)  18	  3.5%
Ser (S)  30	  5.9%
Thr (T)  26	  5.1%
Trp (W)  13	  2.6%
Tyr (Y)  17	  3.3%
Val (V)  37	  7.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 44
Total number of positively charged residues (Arg + Lys): 32

Atomic composition:

Carbon      C	      2614
Hydrogen    H	      4052
Nitrogen    N	       626
Oxygen      O	       705
Sulfur      S	        19

Formula: C2614H4052N626O705S19
Total number of atoms: 8016

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    97205
Abs 0.1% (=1 g/l)   1.732, assuming all pairs of Cys residues form cystines


Ext. coefficient    96830
Abs 0.1% (=1 g/l)   1.725, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.89
This classifies the protein as stable.



Aliphatic index: 117.47

Grand average of hydropathicity (GRAVY): 0.550