ProtParam
User-provided sequence:
10 20 30 40 50 60
MPQSSPSAAA TASDMDKNSG SNSSSASSGS SKGQQPPRSA SAGPAGESKP KSDGKNSNGS
70 80 90 100 110 120
KRYNRKREPS YPKNENFSNQ SRRSNSQKSK TFNKMPPQRG GGSSKPFSSS SNGGRRDEVA
130 140 150 160 170 180
EAQRAEFSPA QFSGPKKINL NHLLNFTFEP RGQAGHFEGS GHGGWGKRNK WGHKPFNKEL
190 200 210 220 230 240
FLQANCQFVV SEDQDYAAHF ADPDTLVNWD FVEQVRICSH EVPSCPICLY PPTAAKITRC
250 260 270 280 290 300
GHIFCWACIL HYLSLSEKTW SKCPICYSSV HKKDLKSVVA TESRQYAVGD TITMQLMKRE
310 320 330 340 350 360
KGVLVALPKS KWVNVDHPIN LGDEQLSQYS KLLLASKEQV LHRVVLEEKG ALEQQLAEEK
370 380 390 400 410 420
HTPESCFIEA AIQEVKIREE ALSGVAGGGG EVTGVVAALE HLVLMAPLAT ESAFQPRKGV
430 440 450 460 470 480
LEYLSAFDDE AAQVCSLDPP GPLALPLVEE EEAVSEPEAC EDAEVADDSL GEGTVGPEMS
490 500 510 520 530 540
QEEPITKPGF TQLSSSPCYY FYQAEDGQHM FLHPVNVRCL VREYGSLEQS PEKISATVVE
550 560 570 580 590 600
IAGYSMSEDV RQRHRYLSHL PLTCEFSICE LALQPPVVSK ETLEMFSDDI EKRKRPTKKK
610 620 630 640 650 660
AREERRRERR IEMEENKRQG RYPEVHIPLE NLQQFPAFNS YTCPSDSALG PTSTEGHGAY
670 680 690 700 710 720
PLSPLSRSPG SHADFLLTPL SPTASQGSPS FCVGSLEDDS PFLSFAQMLR VGKAKADGWP
730 740 750 760 770 780
KTAPKKDDNS LVPPAPVDSD GESDNSDRVP VPSFQNSFSQ AIEAAFMKLD TPATSDPLSE
790 800
DRGGKKRKRQ KQKLLFSTSV VHTK
References and
documentation are available.
Number of amino acids: 804
Molecular weight: 88318.92
Theoretical pI: 6.15
Total number of negatively charged residues (Asp + Glu): 105
Total number of positively charged residues (Arg + Lys): 95
Atomic composition:
Carbon C 3858
Hydrogen H 6048
Nitrogen N 1094
Oxygen O 1223
Sulfur S 31
Formula: C
3858H
6048N
1094O
1223S
31
Total number of atoms: 12254
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 66445
Abs 0.1% (=1 g/l) 0.752, assuming all pairs of Cys residues form cystines
Ext. coefficient 65320
Abs 0.1% (=1 g/l) 0.740, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 62.39
This classifies the protein as unstable.
Aliphatic index: 63.96
Grand average of hydropathicity (GRAVY): -0.642