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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPRDPLIGIV GKPSSGKSTT LNSLTDAGAA VGAFPFTTIE PNQATGYLQV ECACSRFGKE

70 80 90 100 110 120
DLCKPNYGWC SKGKRHIPIK LLDVAGLVPG AHSGRGLGNK FLDDLRHADA LIHVVDVSGT

130 140 150 160 170 180
TDAEGKNTRG YDPLNDIEWL QDEIRLWVEG NLKKRWGSIV RKHTATKSSI VDTLQAQFGG

190 200 210 220 230 240
YGSHAPMIQK ALDRLKGLPP LEKWDDEWIT RVVKSFMMEK FPTVLALNKI DHPDADKNVS

250 260 270 280 290 300
KIMLKYPDTK AVLTSAVTEV FLRKLKKQGF ILYEEGTEFV DTFEDEPDKL KPLDDKILNR

310 320 330 340 350 360
IENIRDLVLY RFGSTGVVQV LQAATDILGL IPVYTVKNIQ TFTGGNGTNV FRDCFLVKRG

370 380 390 400 410
TPVGKVARYI MGGEVTIASI ETVGGVRVSE ESLVEPGKND ILGFKIAPRS A


References and documentation are available.

Number of amino acids: 411 Molecular weight: 45214.01 Theoretical pI: 8.40
Amino acid composition: 
Ala (A) 25 6.1% Arg (R) 20 4.9% Asn (N) 15 3.6% Asp (D) 29 7.1% Cys (C) 5 1.2% Gln (Q) 10 2.4% Glu (E) 22 5.4% Gly (G) 39 9.5% His (H) 7 1.7% Ile (I) 26 6.3% Leu (L) 39 9.5% Lys (K) 34 8.3% Met (M) 6 1.5% Phe (F) 16 3.9% Pro (P) 21 5.1% Ser (S) 20 4.9% Thr (T) 28 6.8% Trp (W) 6 1.5% Tyr (Y) 9 2.2% Val (V) 34 8.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 51 Total number of positively charged residues (Arg + Lys): 54 Atomic composition: Carbon C 2028 Hydrogen H 3238 Nitrogen N 550 Oxygen O 596 Sulfur S 11 Formula: C2028H3238N550O596S11 Total number of atoms: 6423 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 46660 Abs 0.1% (=1 g/l) 1.032, assuming all pairs of Cys residues form cystines Ext. coefficient 46410 Abs 0.1% (=1 g/l) 1.026, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 29.94 This classifies the protein as stable. Aliphatic index: 91.75 Grand average of hydropathicity (GRAVY): -0.222