ProtParam
User-provided sequence:
10 20 30 40 50 60
MPRQFPKLNM SDLDEHVRLL AEKVFAKVLR EEDSKDVMSL FTVPKDCPIG QKEAKERELQ
70 80 90 100 110 120
KELAEQKSVE TAKRKKSFKM IRSQSMSLQM PTQDWKGPPS VSPAMSPTTP LVLGAASKPG
130 140 150 160 170 180
LAPYDMPEYQ RATISGDYCA GITMEDYEQA AKSLAKALMI REKYARLAYH RFPRTTAQYL
190 200 210 220 230 240
AHQGESVPLE EGLPDFHPPP LPQEDPYCLD DAPPNLGYLV RMQGGVLFVY DNQTMLERQE
250 260 270 280 290 300
PHSLPYPDLE TYIVDMSHIL ALITDGPTKT YCHRRLNFLE SKFSLHEMLN EMSEFKELKS
310 320 330 340 350 360
NPHRDFYNVR KVDTHIHAAA CMNQKHLLRF IKYTYQTEPD RTVAEKLGRK ITLRQVFDSL
370 380 390 400 410 420
HMDPYDLTVD SLDVHAGRQT FHGFDKFNSK YNPVGASELR DLYLKTENYL GGEYFARMVK
430 440 450 460 470 480
EVARELEDSK YQYSEPRLSI YGRSPKEWSS LARWFIQHKV YSPNMRWIIQ VPRIYDIFRS
490 500 510 520 530 540
KKLLPSFGKM LENIFLPLFQ ATINPQDHRE LHLFLKYVTG FDSVDDESKH SDHMFSDKSP
550 560 570 580 590 600
SPDLWTSEQN PPYSYYLYYM YANIMVLNNL RRERGLSTFL FRPHCGEAGS ITHLVSAFLT
610 620 630 640 650 660
ADNISHGLLL KKSPVLQYLY YLAQIPIAMS PLSNNSLFLE YSKNPLREFL HKGLHVSLST
670 680 690 700 710 720
DDPMQFHYTK EALMEEYAIA AQVWKLSTCD LCEIARNSVL QSGLSHQEKQ KFLGQNYYKE
730 740 750 760
GPEGNDIRKT NVAQIRMAFR YETLCNELSF LSDAMKSEEI TALAD
References and
documentation are available.
Number of amino acids: 765
Molecular weight: 88483.07
Theoretical pI: 6.55
Total number of negatively charged residues (Asp + Glu): 98
Total number of positively charged residues (Arg + Lys): 92
Atomic composition:
Carbon C 3973
Hydrogen H 6138
Nitrogen N 1060
Oxygen O 1159
Sulfur S 37
Formula: C
3973H
6138N
1060O
1159S
37
Total number of atoms: 12367
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 96080
Abs 0.1% (=1 g/l) 1.086, assuming all pairs of Cys residues form cystines
Ext. coefficient 95580
Abs 0.1% (=1 g/l) 1.080, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 51.97
This classifies the protein as unstable.
Aliphatic index: 77.28
Grand average of hydropathicity (GRAVY): -0.519