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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPSIDCKRLQ KLAPKSPENQ SKCISRLRYM VMLDQVESDE GGNSSTRPYV WAVLLNAPPR

70 80 90 100 110 120
NADEYIRYVR QGPSPMAQKI QNDVSRTLVV ESQFHSRVSQ SSLSRLLNAY VWKRGALYVQ

130 140 150 160 170 180
GMNVLASPFL YACKSENQAF QFFDRLLQNE CPLYVLPNID GVHRGAKLLD KCLEVLDHRL

190 200 210 220 230 240
YTYLLSKGLT AKIYALPSIL TLSACTAPLS EALTIWDFLF AYGIHLNILC VIAQMFIFRE

250 260 270 280 290
QLIDHPSPMT LLRTFPPLNA KNIMKITILL ISKLPPELYN LLARHAWDSE AGVLIDRLT


References and documentation are available.

Number of amino acids: 299 Molecular weight: 33988.71 Theoretical pI: 9.00
Amino acid composition: 
Ala (A) 22 7.4% Arg (R) 18 6.0% Asn (N) 14 4.7% Asp (D) 13 4.3% Cys (C) 7 2.3% Gln (Q) 14 4.7% Glu (E) 12 4.0% Gly (G) 10 3.3% His (H) 6 2.0% Ile (I) 18 6.0% Leu (L) 45 15.1% Lys (K) 14 4.7% Met (M) 8 2.7% Phe (F) 10 3.3% Pro (P) 19 6.4% Ser (S) 24 8.0% Thr (T) 11 3.7% Trp (W) 4 1.3% Tyr (Y) 13 4.3% Val (V) 17 5.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 25 Total number of positively charged residues (Arg + Lys): 32 Atomic composition: Carbon C 1538 Hydrogen H 2443 Nitrogen N 411 Oxygen O 426 Sulfur S 15 Formula: C1538H2443N411O426S15 Total number of atoms: 4833 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41745 Abs 0.1% (=1 g/l) 1.228, assuming all pairs of Cys residues form cystines Ext. coefficient 41370 Abs 0.1% (=1 g/l) 1.217, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 57.93 This classifies the protein as unstable. Aliphatic index: 106.02 Grand average of hydropathicity (GRAVY): 0.005