ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPSNVRSGVL TLLHTACGAG VLAMPFAFKP FGLMPGLITL TFCGICSLCG LLLQTRIAKY 

        70         80         90        100        110        120 
VPKSENASFA KLTQLINPSI SVVFDFAIAV KCFGVGVSYL IIVGDLVPQI VQSIFYRNDD 

       130        140        150        160        170        180 
NMSGSQEHHM FLDRRLYITL IIVFVISPLC FKRSLNSLRY ASMIAIVSVA YLSGLIIYHF 

       190        200        210        220        230        240 
VNRHQLERGQ VYFMVPHGDS QSHSPLTTLP IFVFAYTCHH NMFSVINEQV DKSFKVIRRI 

       250        260        270        280        290        300 
PIFAIVLAYF LYIIIGGTGY MTFGENIVGN ILTLYPNSIS TTIGRLAMLL LVMLAFPLQC 

       310        320        330        340        350        360 
HPCRSSVKNI IIFIENFRKG KLYDNRASFI PLDNFNSEDP QEAPTQQNNE EPNLRSESLR 

       370        380        390        400        410        420 
HINIITLCIL LFSYLLAISI TSLAKVLAIV GATGSTSISF ILPGLFGYKL IGSEFTGTNE 

       430        440        450 
RVPTSIKIFK YLSLSLFIWG IAVMVASLSA IVFLGTSSH 

References and documentation are available.

Number of amino acids: 459

Molecular weight: 50892.04

Theoretical pI: 9.09

Amino acid composition: 
Ala (A)  26	  5.7%
Arg (R)  18	  3.9%
Asn (N)  22	  4.8%
Asp (D)  10	  2.2%
Cys (C)  10	  2.2%
Gln (Q)  13	  2.8%
Glu (E)  13	  2.8%
Gly (G)  29	  6.3%
His (H)  12	  2.6%
Ile (I)  51	 11.1%
Leu (L)  55	 12.0%
Lys (K)  15	  3.3%
Met (M)  12	  2.6%
Phe (F)  33	  7.2%
Pro (P)  21	  4.6%
Ser (S)  44	  9.6%
Thr (T)  24	  5.2%
Trp (W)   1	  0.2%
Tyr (Y)  17	  3.7%
Val (V)  33	  7.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 23
Total number of positively charged residues (Arg + Lys): 33

Atomic composition:

Carbon      C	      2349
Hydrogen    H	      3692
Nitrogen    N	       588
Oxygen      O	       626
Sulfur      S	        22

Formula: C2349H3692N588O626S22
Total number of atoms: 7277

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    31455
Abs 0.1% (=1 g/l)   0.618, assuming all pairs of Cys residues form cystines


Ext. coefficient    30830
Abs 0.1% (=1 g/l)   0.606, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 42.72
This classifies the protein as unstable.



Aliphatic index: 116.58

Grand average of hydropathicity (GRAVY): 0.573