ProtParam
User-provided sequence:
10 20 30 40 50 60
MPSVDIDASQ WQKLTQSREK QTTVITPLGM MMLEIQGELE LPKDFASLAR RDSPNEGRFS
70 80 90 100 110 120
EQDGETLIRF GSLQIDGERA TLFVGKKQRL LGKVTKLDVP MGIMHFNSKD NKVELVDVMK
130
YKVIFKDRPL PIM
References and
documentation are available.
Number of amino acids: 133
Molecular weight: 15168.68
Theoretical pI: 7.95
Total number of negatively charged residues (Asp + Glu): 19
Total number of positively charged residues (Arg + Lys): 20
Atomic composition:
Carbon C 671
Hydrogen H 1097
Nitrogen N 183
Oxygen O 199
Sulfur S 8
Formula: C
671H
1097N
183O
199S
8
Total number of atoms: 2158
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 0.461
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 38.66
This classifies the protein as stable.
Aliphatic index: 87.14
Grand average of hydropathicity (GRAVY): -0.399