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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPTNNTPFLT IFLLFLGLLR FDSFPGLEAA TGKLASIPGL YVFGDSLVDA GNNNYLPISI

70 80 90 100 110 120
SKANYPHNGV DFPNKKPTGR FCNGKNAADA IAEKFGLPLP PPYLSLRGLL KREKRKSAAV

130 140 150 160 170 180
TGVNFASGGA GIFNSSDQKL GQAIPLSKQV NNWLSIHEEV MKLEPSAAQL HLSKSLFTVV

190 200 210 220 230 240
IGSNDLFDYF GSFKLRRQSN PQQYTQLMAD KLKEQLKRIH DSGARRFLII GVAQIGCTPG

250 260 270 280 290 300
KRAKNSTLHE CDEGANMWCS LYNEALVKML QQLKQELQGS ITYTYFDNYK SLHDIISNPA

310 320 330 340 350 360
RYGFADVTSA CCGNGELNAD LPCLPLAKLC SDRTKHLFWD RYGHPTEAAA RTIVDLMLTD

370
DTHYSSPITL TQLVST


References and documentation are available.

Number of amino acids: 376 Molecular weight: 41447.41 Theoretical pI: 8.77
Amino acid composition: 
Ala (A) 30 8.0% Arg (R) 15 4.0% Asn (N) 23 6.1% Asp (D) 20 5.3% Cys (C) 8 2.1% Gln (Q) 15 4.0% Glu (E) 13 3.5% Gly (G) 28 7.4% His (H) 9 2.4% Ile (I) 18 4.8% Leu (L) 47 12.5% Lys (K) 24 6.4% Met (M) 6 1.6% Phe (F) 19 5.1% Pro (P) 21 5.6% Ser (S) 29 7.7% Thr (T) 21 5.6% Trp (W) 3 0.8% Tyr (Y) 13 3.5% Val (V) 14 3.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 33 Total number of positively charged residues (Arg + Lys): 39 Atomic composition: Carbon C 1857 Hydrogen H 2908 Nitrogen N 504 Oxygen O 544 Sulfur S 14 Formula: C1857H2908N504O544S14 Total number of atoms: 5827 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 36370 Abs 0.1% (=1 g/l) 0.877, assuming all pairs of Cys residues form cystines Ext. coefficient 35870 Abs 0.1% (=1 g/l) 0.865, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.41 This classifies the protein as stable. Aliphatic index: 86.20 Grand average of hydropathicity (GRAVY): -0.223