ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPVDQEKLAK LHKLSAANKV GGTRRKINKK GNLYNNNDKD NTKLQAELHK LHPMTIENVA 

        70         80         90        100        110        120 
EANFFKKNGK VLHFNSAVVQ IAPQCNLTMI HGQPKENTLN GLYPSVASQL GSQELEYLTG 

       130        140 
LAHNLENEQT VLDQLGDRCS ETKQQVMNS 

References and documentation are available.

Number of amino acids: 149

Molecular weight: 16619.87

Theoretical pI: 8.85

Amino acid composition: 
Ala (A)  10	  6.7%
Arg (R)   3	  2.0%
Asn (N)  17	 11.4%
Asp (D)   5	  3.4%
Cys (C)   2	  1.3%
Gln (Q)  11	  7.4%
Glu (E)  10	  6.7%
Gly (G)   9	  6.0%
His (H)   6	  4.0%
Ile (I)   4	  2.7%
Leu (L)  18	 12.1%
Lys (K)  15	 10.1%
Met (M)   4	  2.7%
Phe (F)   3	  2.0%
Pro (P)   5	  3.4%
Ser (S)   7	  4.7%
Thr (T)   8	  5.4%
Trp (W)   0	  0.0%
Tyr (Y)   3	  2.0%
Val (V)   9	  6.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 15
Total number of positively charged residues (Arg + Lys): 18

Atomic composition:

Carbon      C	       720
Hydrogen    H	      1171
Nitrogen    N	       213
Oxygen      O	       226
Sulfur      S	         6

Formula: C720H1171N213O226S6
Total number of atoms: 2336

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     4595
Abs 0.1% (=1 g/l)   0.276, assuming all pairs of Cys residues form cystines


Ext. coefficient     4470
Abs 0.1% (=1 g/l)   0.269, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.29
This classifies the protein as stable.



Aliphatic index: 81.81

Grand average of hydropathicity (GRAVY): -0.706