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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPVKILMPAL SPTMKEGTLA KWLVSEGEKI EAGQVIAEIE TDKATMEFEA VDEGVLGKIL

70 80 90 100 110 120
IPAKTAGVKV NQPIAVLLDD GEGEKELKKF LSTIDKPTVT DNKAETSDGD KIKNNPSSLP

130 140 150 160 170 180
ADKQQGRVIA TPLARKIASI NGIDLSLIGS GSGPDGRIVK NDLLKLLDDA PQVQMHGHCT

190 200 210 220 230 240
ETSIPISPMR RVIAQRLVES KQNVPHFYLS VTCYLQHLLS AKKKFYDCLE TKVTVNDFVI

250 260 270 280 290 300
KACAFALDKN PAMNVSWEGE FIRQNQTIDI SVAVAIPDGL ITPIVFSADK LSLSSISDEV

310 320 330 340 350 360
RELVDKAKAG RLQPREFQGG SFTVSNLGMY GIDEFTAIIN PPQAAILAVG AARKVPTVSA

370 380 390 400
DAVVVSDVVT LTLSCDHRVI DGALAARFMQ SLKKAIEDPV IML


References and documentation are available.

Number of amino acids: 403 Molecular weight: 43468.34 Theoretical pI: 5.57
Amino acid composition: 
Ala (A) 38 9.4% Arg (R) 13 3.2% Asn (N) 13 3.2% Asp (D) 28 6.9% Cys (C) 5 1.2% Gln (Q) 15 3.7% Glu (E) 23 5.7% Gly (G) 25 6.2% His (H) 5 1.2% Ile (I) 33 8.2% Leu (L) 37 9.2% Lys (K) 32 7.9% Met (M) 10 2.5% Phe (F) 12 3.0% Pro (P) 22 5.5% Ser (S) 28 6.9% Thr (T) 22 5.5% Trp (W) 2 0.5% Tyr (Y) 4 1.0% Val (V) 36 8.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 51 Total number of positively charged residues (Arg + Lys): 45 Atomic composition: Carbon C 1931 Hydrogen H 3162 Nitrogen N 514 Oxygen O 588 Sulfur S 15 Formula: C1931H3162N514O588S15 Total number of atoms: 6210 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 17210 Abs 0.1% (=1 g/l) 0.396, assuming all pairs of Cys residues form cystines Ext. coefficient 16960 Abs 0.1% (=1 g/l) 0.390, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 31.89 This classifies the protein as stable. Aliphatic index: 103.08 Grand average of hydropathicity (GRAVY): 0.020