ProtParam
User-provided sequence:
10 20 30 40 50 60
MPVSPGEGEV NGGGDVAKND SNSQQSVDGI DAFAACQKPR PDTSSMPVRQ YLDQTVAPIL
70 80 90
LHGLQALARD RPSDPISYLA TYLLKNKNRC DEVKTEEN
References and
documentation are available.
Number of amino acids: 98
Molecular weight: 10601.77
Theoretical pI: 4.78
Total number of negatively charged residues (Asp + Glu): 14
Total number of positively charged residues (Arg + Lys): 10
Atomic composition:
Carbon C 452
Hydrogen H 726
Nitrogen N 132
Oxygen O 154
Sulfur S 4
Formula: C
452H
726N
132O
154S
4
Total number of atoms: 1468
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 4595
Abs 0.1% (=1 g/l) 0.433, assuming all pairs of Cys residues form cystines
Ext. coefficient 4470
Abs 0.1% (=1 g/l) 0.422, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 57.58
This classifies the protein as unstable.
Aliphatic index: 72.65
Grand average of hydropathicity (GRAVY): -0.669