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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPVSPGEGEV NGGGDVAKND SNSQQSVDGI DAFAACQKPR PDTSSMPVRQ YLDQTVAPIL

70 80 90
LHGLQALARD RPSDPISYLA TYLLKNKNRC DEVKTEEN


References and documentation are available.

Number of amino acids: 98 Molecular weight: 10601.77 Theoretical pI: 4.78
Amino acid composition: 
Ala (A) 8 8.2% Arg (R) 5 5.1% Asn (N) 6 6.1% Asp (D) 9 9.2% Cys (C) 2 2.0% Gln (Q) 6 6.1% Glu (E) 5 5.1% Gly (G) 7 7.1% His (H) 1 1.0% Ile (I) 3 3.1% Leu (L) 8 8.2% Lys (K) 5 5.1% Met (M) 2 2.0% Phe (F) 1 1.0% Pro (P) 8 8.2% Ser (S) 8 8.2% Thr (T) 4 4.1% Trp (W) 0 0.0% Tyr (Y) 3 3.1% Val (V) 7 7.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 14 Total number of positively charged residues (Arg + Lys): 10 Atomic composition: Carbon C 452 Hydrogen H 726 Nitrogen N 132 Oxygen O 154 Sulfur S 4 Formula: C452H726N132O154S4 Total number of atoms: 1468 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 4595 Abs 0.1% (=1 g/l) 0.433, assuming all pairs of Cys residues form cystines Ext. coefficient 4470 Abs 0.1% (=1 g/l) 0.422, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 57.58 This classifies the protein as unstable. Aliphatic index: 72.65 Grand average of hydropathicity (GRAVY): -0.669