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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MPVVHVIDVE SGNLQSLTNA IEHLGYEVQL VKSPKDFNIS GTSRLILPGV GNYGHFVDNL

70 80 90 100 110 120
FNRGFEKPIR EYIESGKPIM GICVGLQALF AGSVESPKST GLNYIDFKLS RFDDSEKPVP

130 140 150 160 170 180
EIGWNSCIPS ENLFFGLDPY KRYYFVHSFA AILNSEKKKN LENDGWKIAK AKYGSEEFIA

190 200 210 220 230 240
AVNKNNIFAT QFHPEKSGKA GLNVIENFLK QQSPPIPNYS AEEKELLMND YSNYGLTRRI

250 260 270 280 290 300
IACLDVRTND QGDLVVTKGD QYDVREKSDG KGVRNLGKPV QLAQKYYQQG ADEVTFLNIT

310 320 330 340 350 360
SFRDCPLKDT PMLEVLKQAA KTVFVPLTVG GGIKDIVDVD GTKIPALEVA SLYFRSGADK

370 380 390 400 410 420
VSIGTDAVYA AEKYYELGNR GDGTSPIETI SKAYGAQAVV ISVDPKRVYV NSQADTKNKV

430 440 450 460 470 480
FETEYPGPNG EKYCWYQCTI KGGRESRDLG VWELTRACEA LGAGEILLNC IDKDGSNSGY

490 500 510 520 530 540
DLELIEHVKD AVKIPVIASS GAGVPEHFEE AFLKTRADAC LGAGMFHRGE FTVNDVKEYL

550
LEHGLKVRMD EE


References and documentation are available.

Number of amino acids: 552 Molecular weight: 61068.11 Theoretical pI: 5.33
Amino acid composition: 
Ala (A) 37 6.7% Arg (R) 20 3.6% Asn (N) 30 5.4% Asp (D) 34 6.2% Cys (C) 9 1.6% Gln (Q) 16 2.9% Glu (E) 43 7.8% Gly (G) 50 9.1% His (H) 9 1.6% Ile (I) 33 6.0% Leu (L) 44 8.0% Lys (K) 43 7.8% Met (M) 6 1.1% Phe (F) 24 4.3% Pro (P) 25 4.5% Ser (S) 34 6.2% Thr (T) 22 4.0% Trp (W) 4 0.7% Tyr (Y) 25 4.5% Val (V) 44 8.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 77 Total number of positively charged residues (Arg + Lys): 63 Atomic composition: Carbon C 2733 Hydrogen H 4257 Nitrogen N 723 Oxygen O 834 Sulfur S 15 Formula: C2733H4257N723O834S15 Total number of atoms: 8562 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 59750 Abs 0.1% (=1 g/l) 0.978, assuming all pairs of Cys residues form cystines Ext. coefficient 59250 Abs 0.1% (=1 g/l) 0.970, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 35.61 This classifies the protein as stable. Aliphatic index: 84.22 Grand average of hydropathicity (GRAVY): -0.340