ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQAIADSFSV PNRLVKELQY DNEQNLESDF VTGASQFQRL APSLTVPPIA SPQQFLRAHT 

        70         80         90        100        110        120 
DDSRNPDCKI KIAHGTTTLA FRFQGGIIVA VDSRATAGNW VASQTVKKVI EINPFLLGTM 

       130        140        150        160        170        180 
AGGAADCQFW ETWLGSQCRL HELREKERIS VAAASKILSN LVYQYKGAGL SMGTMICGYT 

       190        200        210        220        230        240 
RKEGPTIYYV DSDGTRLKGD IFCVGSGQTF AYGVLDSNYK WDLSVEDALY LGKRSILAAA 

       250        260        270        280 
HRDAYSGGSV NLYHVTEDGW IYHGNHDVGE LFWKVKEEEG SFNNVIG 

References and documentation are available.

Number of amino acids: 287

Molecular weight: 31636.61

Theoretical pI: 5.82

Amino acid composition: 
Ala (A)  25	  8.7%
Arg (R)  13	  4.5%
Asn (N)  12	  4.2%
Asp (D)  17	  5.9%
Cys (C)   5	  1.7%
Gln (Q)  13	  4.5%
Glu (E)  15	  5.2%
Gly (G)  27	  9.4%
His (H)   7	  2.4%
Ile (I)  16	  5.6%
Leu (L)  23	  8.0%
Lys (K)  14	  4.9%
Met (M)   4	  1.4%
Phe (F)  12	  4.2%
Pro (P)   8	  2.8%
Ser (S)  22	  7.7%
Thr (T)  16	  5.6%
Trp (W)   6	  2.1%
Tyr (Y)  12	  4.2%
Val (V)  20	  7.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 32
Total number of positively charged residues (Arg + Lys): 27

Atomic composition:

Carbon      C	      1410
Hydrogen    H	      2171
Nitrogen    N	       385
Oxygen      O	       427
Sulfur      S	         9

Formula: C1410H2171N385O427S9
Total number of atoms: 4402

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    51130
Abs 0.1% (=1 g/l)   1.616, assuming all pairs of Cys residues form cystines


Ext. coefficient    50880
Abs 0.1% (=1 g/l)   1.608, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 26.26
This classifies the protein as stable.



Aliphatic index: 81.92

Grand average of hydropathicity (GRAVY): -0.231