ProtParam
User-provided sequence:
10 20 30 40 50 60
MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGRP INLGLWDTAG
70 80 90 100 110 120
QEDYDRLRER RLQPVSQTQG YVMAKEIKAV KYLECSALTQ RGLKQVFDEA IRAVLTPPQR
AKKSKCTVL
References and
documentation are available.
Number of amino acids: 129
Molecular weight: 14331.59
Theoretical pI: 8.93
Total number of negatively charged residues (Asp + Glu): 13
Total number of positively charged residues (Arg + Lys): 17
Atomic composition:
Carbon C 634
Hydrogen H 1025
Nitrogen N 175
Oxygen O 188
Sulfur S 7
Formula: C
634H
1025N
175O
188S
7
Total number of atoms: 2029
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 14690
Abs 0.1% (=1 g/l) 1.025, assuming all pairs of Cys residues form cystines
Ext. coefficient 14440
Abs 0.1% (=1 g/l) 1.008, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 34.50
This classifies the protein as stable.
Aliphatic index: 89.15
Grand average of hydropathicity (GRAVY): -0.182