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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGRP INLGLWDTAG

70 80 90 100 110 120
QEDYDRLRPL SYPQTDVFLV CFALNNPASF ENVRAKWYPE VSHHCPNTPI ILVGTKADLR

130 140 150 160 170 180
EDRDTVERLR ERRLQPVSQT QGYVMAKEIK AVKYLECSAL TQRGLKQVFD EAIRAVLTPP

190
QRAKKSKCTV L


References and documentation are available.

Number of amino acids: 191 Molecular weight: 21454.69 Theoretical pI: 8.50
Amino acid composition: 
Ala (A) 15 7.9% Arg (R) 13 6.8% Asn (N) 8 4.2% Asp (D) 11 5.8% Cys (C) 6 3.1% Gln (Q) 9 4.7% Glu (E) 10 5.2% Gly (G) 10 5.2% His (H) 2 1.0% Ile (I) 8 4.2% Leu (L) 17 8.9% Lys (K) 11 5.8% Met (M) 3 1.6% Phe (F) 6 3.1% Pro (P) 12 6.3% Ser (S) 8 4.2% Thr (T) 13 6.8% Trp (W) 2 1.0% Tyr (Y) 8 4.2% Val (V) 19 9.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 21 Total number of positively charged residues (Arg + Lys): 24 Atomic composition: Carbon C 954 Hydrogen H 1518 Nitrogen N 264 Oxygen O 280 Sulfur S 9 Formula: C954H1518N264O280S9 Total number of atoms: 3025 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 23295 Abs 0.1% (=1 g/l) 1.086, assuming all pairs of Cys residues form cystines Ext. coefficient 22920 Abs 0.1% (=1 g/l) 1.068, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.71 This classifies the protein as stable. Aliphatic index: 87.75 Grand average of hydropathicity (GRAVY): -0.245