ProtParam
User-provided sequence:
10 20 30 40 50 60
MQAVERRPSL LFDEYQNSVT KPNETKNKEA RVLSENDGDV SPSVLKQKEI SVDDMDMISL
70 80 90 100 110 120
PTEFDRQMVL GSPMFFDLED EENKIDPLPS VSHHYGNGES DSFVSSYTPS NLKTGEETKD
130 140 150 160 170 180
LFINPFELVS QMRKRYIAAS KQDGISNIKN DTEKWFLYPK PLPKFWRFED DKRFQDPSDS
190 200 210 220 230 240
DLNDDGDSTG TGAATPHRHG YYYPSYFTDH YYYYTKSGLK GKGNIKVPYT GEYFDLEDYK
250 260 270 280 290 300
KQYIYHLSNQ ENTQNPLSPY SSKEESLEEE FLTDVPTFQE FRDDFAYIIE LIQSHKFNEV
310 320 330 340 350 360
SRKRLSYLLD KFELFQYLNS KKEILANKNV PYRDFYNSRK VDRDLSLSGC ISQRQLSEYI
370 380 390 400 410 420
WEKINLEPER IVYQDPETSR KLSLRDIFQF GCSSNDQPIA IGLKLIDDEF LDWYRNIYLI
430 440 450 460 470 480
DYHLTPNKVA KLVGKEMRFY LLAKVFLEFD NFIEGEYLAE IFIKYVIHIL EKSKYQLAQV
490 500 510 520 530 540
SVNFQFYSSG EDWYKKFSQW LLRWKLVSYN IRWNIQIARI FPKLFKENVV SNFQEFLDLI
550 560 570 580 590 600
FNPLFTLEKE QLPIDSSVNT DIIGLQFFLS NVCSMDLVIK ESDEYYWKEF TDMNCKPKFW
610 620 630 640 650 660
TAQGDNPTVA HYMYYIYKSL AKVNFLRSQN LQNTITLRNY CSPLSSRTSQ FGVDLYFTDQ
670 680 690 700 710 720
VESLVCNLLL CNGGLLQVEP LWDTATMIQY LFYLFQIPIL AAPLSSVSLL NSQKSTFLKN
730 740 750 760 770 780
KNVLLEHDYL KDQETAKINP SRDITVGEQR SYETNPFMKM FKMGLKISLS SKSILYNSSY
790 800 810 820 830 840
TLEPLIEEYS VAASIYLLNP TDLCELSRTS VLSSGYEGWY KAHWIGVGVK KAPYFEENVG
850 860 870 880
GIDNWYDTAK DTSIKHNVPM IRRRYRKETL DQEWNFVRDH FGVINSIW
References and
documentation are available.
Number of amino acids: 888
Molecular weight: 104263.90
Theoretical pI: 5.29
Total number of negatively charged residues (Asp + Glu): 124
Total number of positively charged residues (Arg + Lys): 101
Atomic composition:
Carbon C 4752
Hydrogen H 7190
Nitrogen N 1194
Oxygen O 1405
Sulfur S 23
Formula: C
4752H
7190N
1194O
1405S
23
Total number of atoms: 14564
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 173430
Abs 0.1% (=1 g/l) 1.663, assuming all pairs of Cys residues form cystines
Ext. coefficient 172930
Abs 0.1% (=1 g/l) 1.659, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 43.16
This classifies the protein as unstable.
Aliphatic index: 81.31
Grand average of hydropathicity (GRAVY): -0.504