ProtParam
User-provided sequence:
10 20 30 40 50 60
MQEVRNELSR ASTLSVKMAT AGKQFPMVSV FVDPSRKKDK VVAEDGRNCE NSLPIDHSVM
70 80 90 100 110 120
VGIRAVGERL REGVDEDANS YLCLDYDVYL THEPCSMCSM ALIHSRVRRV VFLTEMQRTG
130 140 150 160
SLKLTSGDGY CMNDNKQLNS TYEAFQWIGE EYPVGQVDRD VCC
References and
documentation are available.
Number of amino acids: 163
Molecular weight: 18370.86
Theoretical pI: 5.23
Total number of negatively charged residues (Asp + Glu): 24
Total number of positively charged residues (Arg + Lys): 19
Atomic composition:
Carbon C 785
Hydrogen H 1254
Nitrogen N 226
Oxygen O 252
Sulfur S 15
Formula: C
785H
1254N
226O
252S
15
Total number of atoms: 2532
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 14815
Abs 0.1% (=1 g/l) 0.806, assuming all pairs of Cys residues form cystines
Ext. coefficient 14440
Abs 0.1% (=1 g/l) 0.786, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 32.41
This classifies the protein as stable.
Aliphatic index: 75.21
Grand average of hydropathicity (GRAVY): -0.366