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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQFLGRSISK SIRPSLNSTA RKSWVLSSQQ FLSTSSTESS SRTRGGGGGN RAEKSSEEWP

70 80 90 100 110 120
RPMEVPYQPK IANSIDLIGY VHQPVQFDST LDGKFWAGTV ISHEPSSDSK SESDSSSNFW

130 140 150 160 170 180
IPVLFEGDLA HTANSYLKKN DRVHITGQIL GDVIQSGANS DQAHVQLFKS FHGSFSHQVM

190 200 210 220 230 240
VRDLHYIEGS KAMPKVLPTL DQNEGVLKHS ASVQRGREFG TNLWFDLVDK PNEWCDYREM

250 260 270 280 290 300
KQNGSVNPKH PDFKKKDGSQ ALWLNNAPTE ILSELKDVKF DIPKYAKQPK AGEESWKDLV

310 320 330 340 350 360
DNMNKWWDNR VDKRTPKSPD FKHKETGVGL WLSDSPSWVL EKLPPPKSKT SDIYGVQEMF


References and documentation are available.

Number of amino acids: 360 Molecular weight: 40627.48 Theoretical pI: 7.81
Amino acid composition: 
Ala (A) 14 3.9% Arg (R) 14 3.9% Asn (N) 17 4.7% Asp (D) 25 6.9% Cys (C) 1 0.3% Gln (Q) 17 4.7% Glu (E) 20 5.6% Gly (G) 24 6.7% His (H) 11 3.1% Ile (I) 14 3.9% Leu (L) 26 7.2% Lys (K) 32 8.9% Met (M) 7 1.9% Phe (F) 15 4.2% Pro (P) 22 6.1% Ser (S) 46 12.8% Thr (T) 14 3.9% Trp (W) 12 3.3% Tyr (Y) 7 1.9% Val (V) 22 6.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 45 Total number of positively charged residues (Arg + Lys): 46 Atomic composition: Carbon C 1807 Hydrogen H 2782 Nitrogen N 502 Oxygen O 552 Sulfur S 8 Formula: C1807H2782N502O552S8 Total number of atoms: 5651 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 76430 Abs 0.1% (=1 g/l) 1.881, assuming all pairs of Cys residues form cystines Ext. coefficient 76430 Abs 0.1% (=1 g/l) 1.881, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.44 This classifies the protein as unstable. Aliphatic index: 64.94 Grand average of hydropathicity (GRAVY): -0.760