ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQFPFACLLS TLVISGSLAR ASPFDFIFGN GTQQAQSQSE SQGQVSFTNE ASQDSSTTSL 

        70         80         90        100        110        120 
VTAYSQGVHS HQSATIVSAT ISSLPSTWYD ASSTSQTSVS YASQESDYAV NQNSWSASTN 

       130        140        150        160        170        180 
QLPSTSTTSY YAPTFSTSAD FAASSVNAAS DVSTASVPID TSANSIPFTT TSNIETTTSA 

       190        200        210        220        230        240 
PLTSDTPLIS TSTMSAADNV FSSANPISAS LTTTDSSESF DQTSTAGAIP VQSSADFSSS 

       250        260        270        280        290        300 
SEILVQSSAD FSSPSSPTTT DISLSAAPLQ TSESSSFTTA SAALPVSSTD VDGSSASPVV 

       310        320        330        340        350        360 
SMSAAGQIAS SSSTDNPTMS ETFSLTSTEV DGSDVSSTVS ALLSAPFLQT STSNSFSIVS 

       370        380        390        400        410        420 
PSVSFVPSQS SSDVASSSTA NVVSSSFSDI PPQTSTSGSV VSVAQSASAL AFQSSTEVYG 

       430        440        450        460        470        480 
ASASSTMSSL LSTTSLQSTT LDSSSLASSS ASSSDLTDYG VSSTASIPLL SASEQASTSS 

       490        500        510        520        530        540 
SFSVVSPSVS FVPSQSSSDV ASTSAPSVVS SSFSYTSLQA GGSSMTNPSS STIVYSSSTG 

       550        560        570        580        590        600 
SSEESAASTA SATLSGSSST YMAGNLQSQP PSTSSLLSES QATSTSAVLA SSSVSTTSPY 

       610        620        630        640        650        660 
TTAGGASTEA SSLISSTSAE TSQVSYSQST TALQTSSFAS SSTTEGSETS SQGFSTSSVL 

       670        680        690        700        710        720 
VQMPSSISSE FSPSQTTTQM NSASSSSQYT ISSTGILSQV SDTSVSYTTS SSSVSQVSDT 

       730        740        750        760        770        780 
PVSYTTSSSS VSQVSDTPVS YTTSSSSVSQ VSDTPVSYTT SSSSVSQVSD TPVSYTTSSS 

       790        800        810        820        830        840 
SVSQVSDTSV PSTSSRSSVS QVSDTPVPST SSRSSVSQTS SSLQPTTTSS QRFTISTHGA 

       850        860        870        880        890        900 
LSESSSVSQQ ASEITSSINA TASEYHSIQT TAATQSTTLS FTDANSSSAS APLEVATSTP 

       910        920        930        940        950        960 
TPSSKASSLL LTPSTSSLSQ VATNTNVQTS LTTESTTVLE PSTTNSSSTF SLVTSSDNNW 

       970        980        990       1000       1010       1020 
WIPTELITQA PEAASTASST VGGTQTMTLP HAIAAATQVP EPEGYTLITI GFKKALNYEF 

      1030       1040       1050       1060       1070       1080 
VVSEPKSSAQ IFGYLPEALN TPFKNVFTNI TVLQIVPLQD DSLNYLVSVA EVYFPTAEIE 

      1090       1100       1110       1120       1130       1140 
ELSNLITNSS SAFYTDGMGT AKSMAAMVDS SIPLTGLLHD SNSNSGGSSD GSSSSNSNSG 

      1150       1160       1170       1180       1190       1200 
SSGSGSNSNS GVSSSSGNSY QDAGTLEYSS KSNSNVSTSS KSKKKIIGLV IGVVVGGCLY 

      1210       1220       1230       1240       1250       1260 
ILFMIFAFKY IIRRRIQSQE IIKNPEISSI SSSEFGGEKN YNNEKRMSVQ ESITQSMRIQ 

      1270       1280       1290       1300 
NWMDDSYYGH GLTNNDSTPT RHNTSSSIPK ISRPIASQNS LGWNEV 

References and documentation are available.

Number of amino acids: 1306

Molecular weight: 133114.67

Theoretical pI: 4.06

Amino acid composition: 
Ala (A) 103	  7.9%
Arg (R)  11	  0.8%
Asn (N)  49	  3.8%
Asp (D)  44	  3.4%
Cys (C)   2	  0.2%
Gln (Q)  68	  5.2%
Glu (E)  44	  3.4%
Gly (G)  49	  3.8%
His (H)   8	  0.6%
Ile (I)  53	  4.1%
Leu (L)  69	  5.3%
Lys (K)  16	  1.2%
Met (M)  17	  1.3%
Phe (F)  40	  3.1%
Pro (P)  60	  4.6%
Ser (S) 379	 29.0%
Thr (T) 165	 12.6%
Trp (W)   6	  0.5%
Tyr (Y)  33	  2.5%
Val (V)  90	  6.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 88
Total number of positively charged residues (Arg + Lys): 27

Atomic composition:

Carbon      C	      5642
Hydrogen    H	      8912
Nitrogen    N	      1494
Oxygen      O	      2177
Sulfur      S	        19

Formula: C5642H8912N1494O2177S19
Total number of atoms: 18244

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    82295
Abs 0.1% (=1 g/l)   0.618, assuming all pairs of Cys residues form cystines


Ext. coefficient    82170
Abs 0.1% (=1 g/l)   0.617, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 61.07
This classifies the protein as unstable.



Aliphatic index: 64.30

Grand average of hydropathicity (GRAVY): -0.172