ProtParam
User-provided sequence:
10 20 30 40 50 60
MQIFVKTLTG KTITLEVESS DTIDNVKSKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN
70 80 90 100 110 120
IQKESTLHLV LRLRGGMQIF VKTLTGKTIT LEVESSDTID NVKSKIQDKE GIPPDQQRLI
130 140 150 160 170 180
FAGKQLEDGR TLSDYNIQKE STLHLVLRLR GGMQIFVKTL TGKTITLEVE SSDTIDNVKS
190 200 210 220 230 240
KIQDKEGIPP DQQRLIFAGK QLEDGRTLSD YNIQKESTLH LVLRLRGGMQ IFVKTLTGKT
250 260 270 280 290 300
ITLEVESSDT IDNVKSKIQD KEGIPPDQQR LIFAGKQLED GRTLSDYNIQ KESTLHLVLR
310 320 330 340 350 360
LRGGMQIFVK TLTGKTITLE VESSDTIDNV KSKIQDKEGI PPDQQRLIFA GKQLEDGRTL
370 380
SDYNIQKEST LHLVLRLRGG N
References and
documentation are available.
Number of amino acids: 381
Molecular weight: 42825.94
Theoretical pI: 7.00
Total number of negatively charged residues (Asp + Glu): 55
Total number of positively charged residues (Arg + Lys): 55
Atomic composition:
Carbon C 1879
Hydrogen H 3123
Nitrogen N 527
Oxygen O 598
Sulfur S 5
Formula: C
1879H
3123N
527O
598S
5
Total number of atoms: 6132
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 7450
Abs 0.1% (=1 g/l) 0.174
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 30.11
This classifies the protein as stable.
Aliphatic index: 98.43
Grand average of hydropathicity (GRAVY): -0.521