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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQIKEFRVTL PLTVEEYQVA QLFSVAEASK ENTGGGEGIE VLKNEPFEDF PLLGGKYNSG

70 80 90 100 110 120
QYTYKIYHLQ SKVPAYIRLL APKGSLEIHE EAWNAYPYCR TIITNPKFMK DAFKIIIDTL

130 140 150 160 170 180
HVGDAGDSEN VHELTPDKLK VREVVHIDIA NDPVLPADYK PDEDPTTYQS KKTGRGPLVG

190 200 210 220 230 240
SDWKKHVNPV MTCYKLVTCE FKWFGLQTRV ENFIQKSERR LFTNFHRQVF CSTDRWYGLT

250 260 270
MEDIRAIEDQ TKEELDKARQ VGEVWGMRAD AD


References and documentation are available.

Number of amino acids: 272 Molecular weight: 31302.53 Theoretical pI: 5.60
Amino acid composition: 
Ala (A) 15 5.5% Arg (R) 13 4.8% Asn (N) 10 3.7% Asp (D) 18 6.6% Cys (C) 4 1.5% Gln (Q) 11 4.0% Glu (E) 24 8.8% Gly (G) 17 6.2% His (H) 7 2.6% Ile (I) 15 5.5% Leu (L) 20 7.4% Lys (K) 22 8.1% Met (M) 5 1.8% Phe (F) 12 4.4% Pro (P) 14 5.1% Ser (S) 10 3.7% Thr (T) 18 6.6% Trp (W) 5 1.8% Tyr (Y) 12 4.4% Val (V) 20 7.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 42 Total number of positively charged residues (Arg + Lys): 35 Atomic composition: Carbon C 1408 Hydrogen H 2173 Nitrogen N 373 Oxygen O 418 Sulfur S 9 Formula: C1408H2173N373O418S9 Total number of atoms: 4381 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 45630 Abs 0.1% (=1 g/l) 1.458, assuming all pairs of Cys residues form cystines Ext. coefficient 45380 Abs 0.1% (=1 g/l) 1.450, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 29.38 This classifies the protein as stable. Aliphatic index: 77.02 Grand average of hydropathicity (GRAVY): -0.550