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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQKSILLTKP DGTQSNLHSI KTETPTTVEF DSEQMERGHR ERGRSKKKRG ERDSNVSSLS

70 80 90 100 110 120
RSRSRASSRS RVREEEFLKW TVLRQDPSMR LRVVDVDSEE EGEGNDEDDD DGDGDDMDEE

130 140 150 160 170 180
ESDEEQVSDI ENDLEIDEEF HYDLGMKVLP NFCTSINEVL DSSKPWIAKY EISIRGHENE

190 200 210 220 230 240
DVSLEQLDGG YVRAMQLLTK GAGAEAGNQR SFILYTDLSS ESTYALTYLM GAAVNQGDTV

250 260 270 280 290 300
YIVHWEPSKP TDDSQMFANV ARIRKHVMHL FDCVAGVLDD LDVVVLSLTH PYPKHLLNEM

310 320 330 340
IHGLKPVALC CSLSVILSTL QNFVCSVPIL AVRKKLKRAK RKGISE


References and documentation are available.

Number of amino acids: 346 Molecular weight: 39070.70 Theoretical pI: 4.93
Amino acid composition: 
Ala (A) 15 4.3% Arg (R) 23 6.6% Asn (N) 12 3.5% Asp (D) 31 9.0% Cys (C) 5 1.4% Gln (Q) 11 3.2% Glu (E) 33 9.5% Gly (G) 20 5.8% His (H) 10 2.9% Ile (I) 15 4.3% Leu (L) 33 9.5% Lys (K) 20 5.8% Met (M) 10 2.9% Phe (F) 8 2.3% Pro (P) 11 3.2% Ser (S) 35 10.1% Thr (T) 16 4.6% Trp (W) 3 0.9% Tyr (Y) 8 2.3% Val (V) 27 7.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 64 Total number of positively charged residues (Arg + Lys): 43 Atomic composition: Carbon C 1684 Hydrogen H 2693 Nitrogen N 481 Oxygen O 557 Sulfur S 15 Formula: C1684H2693N481O557S15 Total number of atoms: 5430 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 28670 Abs 0.1% (=1 g/l) 0.734, assuming all pairs of Cys residues form cystines Ext. coefficient 28420 Abs 0.1% (=1 g/l) 0.727, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.86 This classifies the protein as unstable. Aliphatic index: 81.07 Grand average of hydropathicity (GRAVY): -0.603