ProtParam
User-provided sequence:
10 20 30 40 50 60
MQLETQDALY VALELVIAAL AVAGNVLVCA AVGASSALQT PTNYFLVSLA TADVAVGLFA
70 80 90 100 110 120
IPFAITISLG FCTDFHSCLF LACFVLVLTQ SSIFSLLAVA VDRYLAIRVP LRYKGLVTGT
130 140 150 160 170 180
RARGIIAVLW VLAFGIGLTP FLGWNSKDRA TSNCTEPGDG ITNKSCCPVK CLFENVVPMS
190 200 210 220 230 240
YMVYFNFFGC VLPPLLIMMV IYIKIFMVAC KQLQHMELME HSRTTLQREI HAAKSLAMIV
250 260 270 280 290 300
GIFALCWLPV HAINCITLFH PALAKDKPKW VMNVAILLSH ANSVVNPIVY AYRNRDFRYS
310 320 330
FHRIISRYVL CQTDTKGGSG QAGGQSTFSL SL
References and
documentation are available.
Number of amino acids: 332
Molecular weight: 36367.13
Theoretical pI: 8.87
Total number of negatively charged residues (Asp + Glu): 16
Total number of positively charged residues (Arg + Lys): 24
Atomic composition:
Carbon C 1667
Hydrogen H 2624
Nitrogen N 424
Oxygen O 439
Sulfur S 23
Formula: C
1667H
2624N
424O
439S
23
Total number of atoms: 5177
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 39140
Abs 0.1% (=1 g/l) 1.076, assuming all pairs of Cys residues form cystines
Ext. coefficient 38390
Abs 0.1% (=1 g/l) 1.056, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 31.32
This classifies the protein as stable.
Aliphatic index: 113.67
Grand average of hydropathicity (GRAVY): 0.684