ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQLYLTLLFL LSFVECSYIS FISNNADEIL ETDLIETLSY ATLTVGEPYV AQSVVVTRVS 

        70         80         90        100        110        120 
AASHSPLSVS PKNRVSASPI NSQDSDSNTR TAVQLSLSLS NYASQVSQKI SAQTNNDPVT 

       130        140        150        160        170        180 
VSNIYANDNS KSKSSVHNLS SVSGVASVMP SASTMRKVTT LLSQTASTST STLFSSSLSI 

       190        200        210        220        230        240 
SGTQLNGTLL TSVSKGTIDP LVTQMPSYSS QETKIIPSSL TSNKTIYTIS VRTNAATATG 

       250        260        270        280        290        300 
EDSFIASTPA SSTLFYPSNS TQDLVQTLAS TTASPAYPSN RTQITLSPSV SLYSTTSPIY 

       310        320        330        340        350        360 
PSNITENGSS PSPSLSSTVS PVYPSSSTGN ILLSSLFSTV DSSSSPVSST LDTIYVSSSM 

       370        380        390        400        410        420 
QATISSSSSS RQTKTSSSSL STSTSSTATT TENSSTTTIV NLFNAVSTDE PPTVFDRSPN 

       430        440        450        460        470        480 
PMSLADGVSN DGPIQTNKFY TNLIVGSQES PAFVYPYSLW KYTSSSYGFA VQHTTVDQYS 

       490        500        510        520        530        540 
YGGYDSSGNA EYLVNPLGIA HVVFSASNFD SSMTMQVDEM TLSSTRVVLS ESNDSSNYLE 

       550        560        570        580        590        600 
IPLVQGMGFA TGIYHGSLNA KIGSSVGFNT IVSESSSNLA QGILKYRITL LNGVTWLCYV 

       610        620        630        640        650        660 
IGPDDLTSTD FSLEVSSEYE IKASASVDGL IIQLAVAPSE TDYEVFYDQA AGMYVTNFKL 

       670        680        690        700        710        720 
QGVSDGSTAT YEFSYTTQGE SASGSTMIFA LPHHESSFSD IMQDYYTGIQ LASTTKGVMN 

       730        740        750        760        770        780 
GYLTTSLQFS TSLNRQISWL PWSSQLGSNL LEYSKEQLQL LAEVANSELQ VSISESISGL 

       790        800        810        820        830        840 
NTYYLGKVID KYSYILLTVS EIIQDEASTK STLENIKSAF DILLQNEQTY PLIYDTKFNG 

       850        860        870        880        890        900 
LVSSGDWGST STQYDFGNTY YNDHHFHYGY IIHAAAVIGY VDSKLNGTWA ADNKDWVNSL 

       910        920        930        940        950        960 
VRDVANPSEK DEYFAQSRMF DWFNGHSWAA GLYENGNGKN EESSSEDYNF AYAMKLWGAT 

       970        980        990       1000       1010       1020 
IGDQSMELRG DLMISIMKDA MNDYFYYQND NTVEPEEIIG NKVSGILFDN IIDYTTYFGT 

      1030       1040       1050       1060       1070       1080 
NTEYIHGIHM LPITPVSSNI RSETFVEEEW QTKIEPIIES IESGWTGILK LNQALFDPVD 

      1090       1100       1110 
SYAFFSDSTF DSSTYLDNGM SRTWALAFSG GLANSIA 

References and documentation are available.

Number of amino acids: 1117

Molecular weight: 121064.45

Theoretical pI: 4.38

Amino acid composition: 
Ala (A)  66	  5.9%
Arg (R)  16	  1.4%
Asn (N)  66	  5.9%
Asp (D)  55	  4.9%
Cys (C)   2	  0.2%
Gln (Q)  44	  3.9%
Glu (E)  51	  4.6%
Gly (G)  60	  5.4%
His (H)  14	  1.3%
Ile (I)  68	  6.1%
Leu (L)  92	  8.2%
Lys (K)  31	  2.8%
Met (M)  22	  2.0%
Phe (F)  40	  3.6%
Pro (P)  41	  3.7%
Ser (S) 197	 17.6%
Thr (T) 109	  9.8%
Trp (W)  13	  1.2%
Tyr (Y)  61	  5.5%
Val (V)  69	  6.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 106
Total number of positively charged residues (Arg + Lys): 47

Atomic composition:

Carbon      C	      5348
Hydrogen    H	      8217
Nitrogen    N	      1347
Oxygen      O	      1807
Sulfur      S	        24

Formula: C5348H8217N1347O1807S24
Total number of atoms: 16743

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   162515
Abs 0.1% (=1 g/l)   1.342, assuming all pairs of Cys residues form cystines


Ext. coefficient   162390
Abs 0.1% (=1 g/l)   1.341, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 44.13
This classifies the protein as unstable.



Aliphatic index: 79.69

Grand average of hydropathicity (GRAVY): -0.166