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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQNAQIKSSS KGSGIDGTDR NSKDGVEKRP LEDVKQMIDA GTPDVGHKST VETKPNVGWQ

70 80 90 100 110 120
ASHSNLAALH EKEQKYEMEH HHARHKLHRQ VIPDYTSAST AMFSDCMFNA APDKVRSLST

130 140 150 160 170 180
MKSSGLSPKH PFNVVATFKG PFPQHSVESK PLDGGYSAKD HFPSFKMLQA QQHPAHRHYK

190 200 210 220 230 240
DNDKYGLKSP SRSFVKDKKR LVHRFLKSME PSSSGQSKDS SALAPAFDPI LPNVISKPSK

250 260 270 280 290 300
RPTHHSHSSD GSSSTQTDIS LQSLLYHDLE SSPKKHVSPS RPPSVASESS PAVANPIGLS

310 320 330 340 350 360
PKDACNASFS QSSSSSLSSS SSSSSSTSFS QSVAVDPLEP PGNITYSSSN LSLNSDELDY

370 380 390 400 410 420
YQRHIGLQLQ QTEALLKHSL KDEVLKDEND LVKNIANFDK IVKELRDLRS RTIGWKELVE

430 440 450 460 470 480
EDYLMNLKQD FDKENPESFE ARLSDTINTN VAKLQDLEKR MASCKDRLAS RKEVMRKMES

490 500 510 520
LLSLENSLMI SKKNVTFASK YRNEALDIVF LIIIIVICYT FKHLVSHK


References and documentation are available.

Number of amino acids: 528 Molecular weight: 58750.03 Theoretical pI: 8.88
Amino acid composition: 
Ala (A) 31 5.9% Arg (R) 21 4.0% Asn (N) 23 4.4% Asp (D) 35 6.6% Cys (C) 4 0.8% Gln (Q) 21 4.0% Glu (E) 28 5.3% Gly (G) 18 3.4% His (H) 24 4.5% Ile (I) 21 4.0% Leu (L) 46 8.7% Lys (K) 49 9.3% Met (M) 13 2.5% Phe (F) 18 3.4% Pro (P) 30 5.7% Ser (S) 85 16.1% Thr (T) 19 3.6% Trp (W) 2 0.4% Tyr (Y) 12 2.3% Val (V) 28 5.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 63 Total number of positively charged residues (Arg + Lys): 70 Atomic composition: Carbon C 2562 Hydrogen H 4080 Nitrogen N 734 Oxygen O 815 Sulfur S 17 Formula: C2562H4080N734O815S17 Total number of atoms: 8208 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 29130 Abs 0.1% (=1 g/l) 0.496, assuming all pairs of Cys residues form cystines Ext. coefficient 28880 Abs 0.1% (=1 g/l) 0.492, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 56.93 This classifies the protein as unstable. Aliphatic index: 70.74 Grand average of hydropathicity (GRAVY): -0.688