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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQNPYGHFTN NTTEDREASS QGGPFGQSLN RPLDYAGSFP SLTYNNNNFI ANQQPSLPLP

70 80 90 100 110 120
EPRLSWNNVN QVSNPLMVTP LPGLQKRMNK NIKKKLPRVS KKASALSNGV SGNVMSNSNI

130 140 150 160 170 180
VGHGAVGSAS GWKVEMGGSD ELERRKRRAE RFSQGPSATT NSNDNLNEDF ANLNAISSKS

190 200 210 220 230 240
HQYDKKIHVV GRCQTLEKSY LRLTSEPNPD LIRPPNILQK MYCLLMDKYQ SKTATYTYLC

250 260 270 280 290 300
DQFKSMRQDL RVQMIENSFT IKVYQTHARI ALENGDLGEF NQCQNRIMAL FENPTIPKKS

310 320 330 340 350 360
YSEFICYSVL YSMLTEDYPS ISHLKLKLID DGSSEILEDE HVKMIFELSD MKLVGNYHYF

370 380 390 400 410 420
MKNYLKLHKF EKCLINSFLN LEKLIFLTII CKSYNQVNLD FVKSEFNFNS IEETTNFLNE

430 440 450 460 470
QNLTEFILNK QITDSNGKSS NIKILNTKGC RVQLIQNYMK SKKIDIKGQK


References and documentation are available.

Number of amino acids: 470 Molecular weight: 53719.20 Theoretical pI: 9.10
Amino acid composition: 
Ala (A) 15 3.2% Arg (R) 18 3.8% Asn (N) 48 10.2% Asp (D) 19 4.0% Cys (C) 8 1.7% Gln (Q) 24 5.1% Glu (E) 27 5.7% Gly (G) 23 4.9% His (H) 9 1.9% Ile (I) 29 6.2% Leu (L) 47 10.0% Lys (K) 40 8.5% Met (M) 15 3.2% Phe (F) 21 4.5% Pro (P) 20 4.3% Ser (S) 45 9.6% Thr (T) 22 4.7% Trp (W) 2 0.4% Tyr (Y) 19 4.0% Val (V) 19 4.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 46 Total number of positively charged residues (Arg + Lys): 58 Atomic composition: Carbon C 2371 Hydrogen H 3750 Nitrogen N 656 Oxygen O 721 Sulfur S 23 Formula: C2371H3750N656O721S23 Total number of atoms: 7521 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 39810 Abs 0.1% (=1 g/l) 0.741, assuming all pairs of Cys residues form cystines Ext. coefficient 39310 Abs 0.1% (=1 g/l) 0.732, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.12 This classifies the protein as stable. Aliphatic index: 77.98 Grand average of hydropathicity (GRAVY): -0.584