ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQRHVFARNF RRLSLLRNPS LTKRFQSSAS GAANTPNNND EVMLLQQKLL YDEIRSELKS 

        70         80         90        100        110        120 
LSQVPEDEIL PELKKSLEQD KLSDKEQQLE AELSDFFRNY ALLNKLFDSK TLDGQSSTTT 

       130        140        150        160        170        180 
AAATPTKPYP NLIPSANDKP YSSQELFLRQ LNHSMRTAKL GATISKVYYP HKDIFYPPLP 

       190        200        210        220        230        240 
ENITVESLMS AGVHLGQSTS LWRSSTQSYI YGEYKGIHII DLNQTLSYLK RAAKVVEGVS 

       250        260        270        280        290        300 
ESGGIILFLG TRQGQKRGLE EAAKKTHGYY VSTRWIPGTL TNSTEISGIW EKQEIDSNDN 

       310        320        330        340        350        360 
PTERALSPNE TSKQVKPDLL VVLNPTENRN ALLEAIKSRV PTIAIIDTDS EPSLVTYPIP 

       370        380        390 
GNDDSLRSVN FLLGVLARAG QRGLQNRLAR NNEK 

References and documentation are available.

Number of amino acids: 394

Molecular weight: 44151.86

Theoretical pI: 8.74

Amino acid composition: 
Ala (A)  24	  6.1%
Arg (R)  23	  5.8%
Asn (N)  25	  6.3%
Asp (D)  18	  4.6%
Cys (C)   0	  0.0%
Gln (Q)  20	  5.1%
Glu (E)  27	  6.9%
Gly (G)  20	  5.1%
His (H)   6	  1.5%
Ile (I)  21	  5.3%
Leu (L)  49	 12.4%
Lys (K)  25	  6.3%
Met (M)   4	  1.0%
Phe (F)  10	  2.5%
Pro (P)  22	  5.6%
Ser (S)  40	 10.2%
Thr (T)  26	  6.6%
Trp (W)   3	  0.8%
Tyr (Y)  14	  3.6%
Val (V)  17	  4.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 45
Total number of positively charged residues (Arg + Lys): 48

Atomic composition:

Carbon      C	      1951
Hydrogen    H	      3130
Nitrogen    N	       548
Oxygen      O	       610
Sulfur      S	         4

Formula: C1951H3130N548O610S4
Total number of atoms: 6243

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    37360
Abs 0.1% (=1 g/l)   0.846

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 53.50
This classifies the protein as unstable.



Aliphatic index: 87.89

Grand average of hydropathicity (GRAVY): -0.555